Taishan Pinus massoniana Pollen Polysaccharides Enhance Immune Responses in Chickens Infected by Avian Leukosis Virus Subgroup B

Immunological Investigations
Shifa YangRuiliang Zhu

Abstract

Immunosuppressive virus, which can cause suppressed immunity and vaccination failure, frequently occurs in chicken flocks and seriously destroys the poultry industry. Our previous studies have reported that Taishan Pinus massoniana pollen polysaccharide (TPPPS) possess immunomodulatory effects and improve the immune effects of vaccines. In this study, avian leukosis virus subgroup B (ALV-B) was chosen as immunosuppressive virus to artificially establish immunosuppressive models in chickens, and the immune modulatory ability of TPPPS on the immune response of chickens was evaluated. Four randomly assigned groups (Group I-IV) of these immunosuppressed chickens were administered with TPPPS at doses of 0, 100, 200, and 400 mg/kg (every kilogram chick), respectively. Group V was administered with saline as control. At seven day old, 10 chickens randomly selected from Group I-V were inoculated with the attenuated Newcastle disease (ND) vaccine. The results showed that during the monitoring period, TPPPS significantly enhanced weight of immune organs, peripheral lymphocyte proliferation, the percentage of CD4+ and the ratio of CD4+/CD8+, IL-2 and IFN-γ production, and ALV-B antibody positive rate of chickens in a dose-dependent manner...Continue Reading

References

Jun 1, 1993·Immunology Today·F M Audibert, L D Lise
Aug 26, 1998·Poultry Science·L N Payne
Oct 24, 2000·Journal of Immunological Methods·J WaloryW Hryniewicz
Feb 28, 2001·Proceedings of the National Academy of Sciences of the United States of America·J StrongN Killeen
May 1, 2004·Journal of Medicinal Food·Tae-Soo LimJae-Kwan Hwang
Mar 1, 2005·Veterinary Immunology and Immunopathology·Raadan OdbilegMisao Onuma
Jul 15, 2006·International Journal of Biological Macromolecules·Tiehong YangQibing Mei
Mar 4, 2008·Cellular Immunology·Cheng-Rui LiDavid D Lo
Oct 8, 2009·Natural Product Research·Jian-Min Xing, Fen-Fang Li
Apr 23, 2010·Avian Diseases·Frederic J Hoerr
Apr 1, 2011·The Journal of General Virology·Shao-Zhen FengMing Liao
Feb 14, 2013·International Journal of Biological Macromolecules·Guolin CuiRuiliang Zhu
Apr 22, 2016·Immunological Investigations·Paulo Germano de CarvalhoAparecida Tiemi Nagao-Dias
Jun 3, 2016·Frontiers in Microbiology·Min FengXiquan Zhang
Jul 16, 2016·Immunological Investigations·Maryam AzimiEisa Salehi
Jul 28, 2016·Journal of Virological Methods·Sabari Nath NeerukondaMark S Parcells

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