Abstract
Takayasu arteritis is a chronic inflammatory vasculitis of unknown origin affecting large vessels, predominantly the aorta and its main branches. Vessel inflammation leads to wall thickening, fibrosis, and stenosis. The lesions are often asymptomatic leading to limb numbness, transient ischemic attack, cardiovascular event and renovascular hypertension. Treatment is based on corticosteroids, immunosuppressant and biologics if necessary. Endovascular treatment and open-surgery can be useful for end-organ ischemia relief.
References
Jan 17, 2002·Rheumatology·F Numano
Sep 28, 2006·Human Immunology·G Saruhan-DireskeneliUNKNOWN Rheumatology Education and Research Society Vasculitis Study Group
Apr 17, 2008·Annals of the Rheumatic Diseases·C MukhtyarUNKNOWN European Vasculitis Study Group
Jan 16, 2010·Medicine·Laurent ArnaudZahir Amoura
Jun 15, 2010·Rheumatology·Sibel Z AydinHaner Direskeneli
Oct 5, 2011·Annals of Internal Medicine·Lorenzo DagnaMaria Grazia Sabbadini
Jan 11, 2012·Circulation·David SaadounPatrice Cacoub
Feb 14, 2012·Arthritis Care & Research·Jean SchmidtKenneth J Warrington
Aug 22, 2012·BMC Infectious Diseases·María Elena SotoRicardo Gamboa
Jul 9, 2013·American Journal of Human Genetics·Güher Saruhan-DireskeneliAmr H Sawalha
Oct 17, 2013·The Journal of Rheumatology·Cloé ComarmondDavid Saadoun
Jan 16, 2014·The American Journal of Cardiology·Cloé ComarmondDavid Saadoun
Jan 22, 2015·Arthritis & Rheumatology·D SaadounP Cacoub
Sep 1, 2015·Arthritis & Rheumatology·C ComarmondUNKNOWN French Takayasu Network
Sep 12, 2015·Circulation·Arsene MekinianUNKNOWN French Takayasu Network