PMID: 7008897Feb 1, 1981Paper

Taking cell cultures to the patient in an attempt to improve chlamydial isolation

The British Journal of Venereal Diseases
Y F NgeowD Taylor-Robinson

Abstract

McCoy cell cultures were inoculated with 121 urethral and cervical specimens taken from patients attending one of two sexually transmitted disease clinics. The mean number of Chlamydia trachomatis inclusions was greater when the cultures were inoculated with the specimens and centrifuged in the clinic than when the specimens were first stored in liquid nitrogen. Furthermore, 18 of the 29 chlamydia-positive specimens produced larger numbers of of inclusions when inoculated immediately. Despite this, the isolation rate from specimens inoculated directly (22%) was about the same as from specimens which had been frozen (21%). Of the 30 occasions on which the cell monolayers were disrupted, 29 followed immediate inoculation. This may possibly have been due to some toxic factor in some of the specimens.

References

Sep 1, 1979·Recenti progressi in medicina·A MorelliM A Pelli
Jul 1, 1977·Journal of Clinical Microbiology·M J Prentice, J Farrant
Mar 1, 1980·Journal of Clinical Pathology·D Taylor-Robinson, B J Thomas

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Citations

Aug 1, 1991·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·B ThomasD Taylor-Robinson
May 1, 1997·Journal of Pediatric and Adolescent Gynecology·S P ReddyR Slupik
Aug 1, 1982·The British Journal of Venereal Diseases·G L RidgwayJ D Oriel

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