Taking the guesswork out of supplying multicompartment compliance aids: do pharmacists require further guidance on medication stability?

The International Journal of Pharmacy Practice
Julia Fiona-Maree GilmartinMine Orlu-Gul

Abstract

The purpose of this article is to identify information that is currently available to pharmacists concerning the stability of medications repackaged into multicompartment compliance aids (MCAs). This article explores the potential risks associated with repackaging medications into MCAs for pharmacists who supply and patients who use them. There is a paucity of information currently available to pharmacists concerning the stability of medications repackaged into MCAs as it is not routinely provided by pharmaceutical manufacturers. However, some studies have identified the potential for adverse effects on safety, bioavailability and stability that may have a clinical impact. There are also professional and legal implications of removing medications from their original packaging for storage in MCAs. There is a growing need for further information concerning the stability of medications repackaged into MCAs to guide pharmacists who are supplying these compliance aids to primary and secondary care. Pharmaceutical manufacturers and researchers should be advised to conduct stability testing in MCAs for orally administered medications. This information should be readily available, and pharmacists should be made aware of it via their ph...Continue Reading

References

Mar 3, 2009·Journal of Clinical Pharmacy and Therapeutics·B GlassA Haywood
Sep 14, 2010·Journal of Clinical Pharmacy and Therapeutics·P Donyai
Jan 13, 2012·The International Journal of Pharmacy Practice·Stephen PerksBeverley Glass

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Citations

May 25, 2018·Expert Opinion on Drug Delivery·Estela R GarcíaEduardo L Mariño
Jul 18, 2017·Journal of Pharmaceutical Health Services Research : an Official Journal of the Royal Pharmaceutical Society of Great Britain·Bahijja Tolulope Raimi-AbrahamMine Orlu
Oct 11, 2017·Drugs & Therapy Perspectives : for Rational Drug Selection and Use·Valerie AlbertIsabelle Arnet

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