Takotsubo cardiomyopathy with involvement of delayed-onset rhabdomyolysis and acute kidney injury after rosuvastatin treatment

Internal Medicine
Tomohito KamadaHideo Izawa

Abstract

Takotsubo cardiomyopathy is a disorder characterized by left ventricular apical ballooning with preceding emotional and/or physical stressors. This condition is also an important differential diagnosis of acute coronary syndrome. We herein describe a case of Takotsubo cardiomyopathy, a significant clinical phenomenon, triggered by delayed-onset rhabdomyolysis following the administration of long-term statin treatment, without any preceding stressors or changes in the patient's medical condition, in association with complaints of non-specific muscle-related symptoms. Although an electrocardiogram showed remarkable ST-segment elevation, a careful reading of the electrocardiogram findings revealed the features of Takotsubo cardiomyopathy. Withdrawing the statin therapy improved the patient's cardiac function.

References

Feb 3, 2006·Cardiovascular Drugs and Therapy·Eric BruckertBernard Bégaud
Feb 24, 2006·Clinical Therapeutics·Matthew A SilvaGary R Tataronis

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Citations

Sep 4, 2015·Internal Medicine·Josef Finsterer, Marlies Frank
Mar 7, 2015·Internal Medicine·Satoshi Kurisu, Yasuki Kihara
May 12, 2017·Journal of Cardiovascular Pharmacology and Therapeutics·Kazuhiko Kido, Maya Guglin

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