Talbot multi-focal holographic fluorescence endoscopy for optically sectioned imaging

Optics Letters
Chen Yen LinYuan Luo

Abstract

A wide-field multi-plane endoscopic system incorporating multiplexed volume holographic gratings and Talbot illumination to simultaneously acquire optically sectioned fluorescence images of tissue structures from different depths is presented. The proposed endoscopic system is configured such that multiple Talbot-illumination planes occur inside a volumetric sample and serve as the input focal planes for the subsequent multiplexed volume holographic imaging gratings. We describe the design, implementation, and experimental data demonstrating this endoscopic system's ability to obtain optically sectioned multi-plane fluorescent images of tissue samples in wide-field fashion without scanning in lateral and axial directions.

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Citations

Aug 30, 2016·Biomedical Optics Express·Yanlu LvJianwen Luo
Mar 16, 2019·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Sunil VyasYuan Luo

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