PMID: 377165Jul 1, 1979Paper

Tamoxifen-induced regression of benign breast lesions

Obstetrics and Gynecology
I Ricciardi, A Ianniruberto

Abstract

Sixty-three patients with severe breast dysplasia were treated with tamoxifen, 10 mg/day from day 5 to day 25 of the menstrual cycle for 4 months. Lesions were assessed by mammography, thermography, and echography (A- and B-mode scanning). In 45 patients (71.43%) there was complete remission of symptoms and disappearance of lesions as assessed by echography and clinical examination. Some improvement was seen in 12 patients. In all but 2 of those in whom lesions disappeared completely, no recurrence was seen in 12 months after treatment was discontinued. Estrogen receptors were assayed in 10 patients, but were detected in none. A decrease of doubtful statistical significance was observed in some patients in basal and thyrotropin-releasing hormone (TRH)-stimulated levels of prolactin during the treatment period. No other significant or unequivocal change in endocrine parameters was observed during tamoxifen treatment.

Citations

Jan 1, 1984·Pharmacology & Therapeutics·B J Furr, V C Jordan
Jul 1, 1982·The British Journal of Radiology·A HellebergS Sander
Apr 17, 1998·Clinical Imaging·J L HurstJ P Hogg
May 1, 1987·The American Journal of the Medical Sciences·F J Hendler
Jan 1, 1988·Acta Obstetricia Et Gynecologica Scandinavica·I E Messinis, D Lolis
Mar 1, 1982·Journal of the American Geriatrics Society·R B GreenblattC Nezhat
Sep 1, 1989·Journal of Adolescent Health Care : Official Publication of the Society for Adolescent Medicine·J R Griffith
Jan 14, 2004·The Breast Journal·Priscilla J SlanetzJeffrey B Mendel
Jan 1, 1986·Annals of the New York Academy of Sciences·L DogliottiA Angeli
Jul 24, 1998·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·E KontostolisD Lolis
Sep 1, 1993·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·F R Pérez-López, C Blasco Comenge
Feb 26, 1998·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·E KontostolisD Lolis
Mar 1, 1982·Postgraduate Medicine·R B GreenblattC Samaras

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.