PMID: 1354413Sep 1, 1992

Tardive dyskinesia in elderly psychiatric patients: a 5-year study

The American Journal of Psychiatry
R YassaM Thibeau

Abstract

The authors investigated the prevalence of tardive dyskinesia among elderly psychiatric patients who had never received neuroleptic medication before their first hospitalization. The study was performed in the geriatric psychiatry unit of a university-affiliated hospital in Canada and involved all first-admission patients admitted from September 1984 through August 1989 who had never taken neuroleptic drugs. In September and October 1989, the patients who were available for follow-up were examined and given ratings on the Abnormal Involuntary Movement Scale to establish the presence or absence of tardive dyskinesia. The patients' records were reviewed for information on age, diagnosis, duration of hospitalization, neuroleptic treatment received after admission, anticholinergic drugs received, and drug-free periods. Of the 162 patients who were available and whose data were analyzed, a total of 99 had been treated with neuroleptics, and 35 (35.4%) of these were found to have tardive dyskinesia. Two of the 35 also had tardive dystonia. Significantly more patients with major depression than patients with primary degenerative dementia or delusional psychosis had tardive dyskinesia. This study confirms the higher vulnerability of el...Continue Reading

Citations

Dec 7, 2013·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Leslie J CloudStewart A Factor
Mar 10, 2006·The Consultant Pharmacist : the Journal of the American Society of Consultant Pharmacists·Jack J Chen, Kelly C Lee
Nov 4, 2006·Der Nervenarzt·W W Fleischhacker, W Hummer
Sep 22, 2005·Australasian Psychiatry : Bulletin of Royal Australian and New Zealand College of Psychiatrists·Peter Herriot, Kamran Kheirani
Mar 1, 1997·The Psychiatric Clinics of North America·M L CattersonR L Martin
May 30, 2013·BMC Psychiatry·Ray M MerrillPaul M Matiaco
Dec 6, 2005·The Psychiatric Clinics of North America·Robert C Young
Dec 19, 2001·International Journal of Geriatric Psychiatry·G FabbriniC Aurilia
Apr 22, 2011·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Margaret G WoernerJohn M Kane
Apr 7, 2005·International Clinical Psychopharmacology·Raphael M BonelliHans-Peter Kapfhammer
Jul 13, 2017·Expert Opinion on Pharmacotherapy·Lauren C Seeberger, Robert A Hauser
Aug 30, 2019·Journal of Comparative Effectiveness Research·Saurabh AggarwalChuck Yonan

Related Concepts

Diagnosis, Psychiatric
Delusions
Senile Paranoid Dementia
Melancholia
Dyskinesia, Medication-Induced
Dystonia, Paroxysmal
Hospitalization
Antipsychotic Effect

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