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Target Controlled Infusion of cefepime in critically ill patients: single center experience

Antimicrobial Agents and Chemotherapy

Nov 4, 2019

Stijn JonckheerePieter J Colin

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Abstract

Attainment of appropriate pharmacokinetic-pharmacodynamic (PK-PD) targets for antimicrobial treatment is challenging in critically ill patients, particularly for cefepime, which exhibits a relative narrow therapeutic-toxic window compared to other beta-lactam antibiotics. Target Control...read more

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Alcohol dehydrogenase
Analgesics
Anesthesia Procedures
Clinical Trials
Creatinine
Intensive Care Unit
Monobactams
Drug Kinetics
Plasma
Mass Spectrometry
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Target Controlled Infusion of cefepime in critically ill patients: single center experience

Antimicrobial Agents and Chemotherapy

Nov 4, 2019

Stijn JonckheerePieter J Colin

PMID: 31685467

DOI: 10.1128/aac.01552-19

Abstract

Attainment of appropriate pharmacokinetic-pharmacodynamic (PK-PD) targets for antimicrobial treatment is challenging in critically ill patients, particularly for cefepime, which exhibits a relative narrow therapeutic-toxic window compared to other beta-lactam antibiotics. Target Control...read more

Mentioned in this Paper

Alcohol dehydrogenase
Analgesics
Anesthesia Procedures
Clinical Trials
Creatinine

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