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Target lipidomics approach to reveal the resolution of inflammation induced by Chinese medicine combination in Liu-Shen-Wan against realgar overexposure to rats

Journal of Ethnopharmacology

Aug 24, 2019

Jiaojiao WangJinao Duan

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PubMed

Abstract

Liu-Shen-Wan (LSW) is one of the popular over-the-counter drugs in Asia, which contains realgar (As4S4), used for the treatment of upper respiratory tract inflammation and skin infections. However, the safety and potential risk of this arsenic remain unknown. The aim of this study was t...read more

Mentioned in this Paper

Study
Cyclooxygenase 2
Arsenic Poisoning
Cytochrome P450
Tetraarsenic tetrasulfide
Arsenic
Liu-Shen-Wan
Eicosanoids
Medicine, Chinese
Pharmacologic Substance
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Target lipidomics approach to reveal the resolution of inflammation induced by Chinese medicine combination in Liu-Shen-Wan against realgar overexposure to rats

Journal of Ethnopharmacology

Aug 24, 2019

Jiaojiao WangJinao Duan

PMID: 31442622

DOI: 10.1016/j.jep.2019.112171

Abstract

Liu-Shen-Wan (LSW) is one of the popular over-the-counter drugs in Asia, which contains realgar (As4S4), used for the treatment of upper respiratory tract inflammation and skin infections. However, the safety and potential risk of this arsenic remain unknown. The aim of this study was t...read more

Mentioned in this Paper

Study
Cyclooxygenase 2
Arsenic Poisoning
Cytochrome P450
Tetraarsenic tetrasulfide
Arsenic
Liu-Shen-Wan
Eicosanoids
Medicine, Chinese
Pharmacologic Substance

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Anti-inflammatory Treatments

A drug or substance that reduces inflammation (redness, swelling, and pain) in the body. Anti-inflammatory agents block certain substances in the body that cause inflammation and swelling. Discover the latest research on anti-inflammatory treatments here

Mechanisms of CYP450

Cytochrome P450 (CYP450) are a family of enzymes involved in two major processes, such as the synthesis of fatty acids, steroids, and biles acids, and the metabolism of toxins and drugs. Discover the latest research on the Mechanisms of CYP450 enzymes here.

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Realgar and realgar-containing Liu-Shen-Wan are less acutely toxic than arsenite and arsenate

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Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)

Health risk assessment of arsenic in Realgar and NiuHuangJieDu Tablets based on pharmacokinetic study

Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)May 19, 2018
Xiao WuTaijun Hang
Paper Details
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