Target-organ damage in stage I hypertensive subjects with white coat and sustained hypertension: results from the HARVEST study

Hypertension
P PalatiniA C Pessina

Abstract

Controversy remains on whether white coat hypertension is a benign clinical condition or carries an increased risk of target-organ damage. Nine hundred forty-two stage I hypertensive subjects enrolled in the HARVEST trial underwent 24-hour ambulatory blood pressure monitoring and urine collection for albumin measurement. Reliable echocardiographic data were obtained in 722 subjects. White coat hypertensive subjects were defined on the basis of three different partition values: mean daytime blood pressure <130/90 mm Hg, <135/85 mm Hg, or <140/90 mm Hg. Ninety-five normotensive subjects with similar age and sex distribution were studied as controls. With all threshold levels, left ventricular mass index and wall thicknesses were greater in the sustained hypertensive subjects than in the white coat hypertensive subjects, also when these differences were adjusted for blood pressure readings taken in the office. Relative wall thickness was similar in the two hypertensive groups. All echocardiographic dimensional data were greater in the white coat hypertensive subjects than in the normotensive subjects. Urinary albumin and the prevalence of microalbuminuria were also greater in the sustained hypertensive subjects than in the white c...Continue Reading

References

Sep 1, 1992·Archives of Internal Medicine·P PalatiniA C Pessina
Jan 1, 1992·Clinical and Experimental Hypertension. Part A, Theory and Practice·S JuliusN Schork
Mar 1, 1992·European Heart Journal·P PalatiniC Dal Palù
Apr 1, 1991·European Heart Journal·P GoslingJ P Fox
Feb 10, 1989·JAMA : the Journal of the American Medical Association·W B WhiteH M Dey
Feb 15, 1986·The American Journal of Cardiology·R B DevereuxN Reichek
Jan 8, 1988·JAMA : the Journal of the American Medical Association·T G PickeringJ H Laragh
Jan 1, 1993·Drugs·J Ocón-Pujadas, J Mora-Maciá
Mar 15, 1995·Journal of the American College of Cardiology·H M KrumholzD Levy
Apr 1, 1994·American Journal of Hypertension·K MartinL R Krakoff
Nov 1, 1993·Hypertension·P GosseJ Clementy

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Citations

Oct 6, 2011·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Tomáš SeemanUlrike John
Sep 12, 2000·Current Hypertension Reports·P Palatini
Sep 12, 2000·Current Hypertension Reports·S G Chrysant
Jul 14, 2001·Journal of the American College of Cardiology·K KarioT G Pickering
Jul 10, 2002·Journal of the American College of Cardiology·Paul A SmithDavid A S G Mary
Apr 25, 2009·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Kei AsayamaYutaka Imai
Jun 11, 2010·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Gil F SallesClaudia R L Cardoso
May 28, 2010·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Gregory VyssoulisChristodoulos Stefanadis
Jun 11, 2002·Blood Pressure Monitoring·S D PierdomenicoA Mezzetti
Apr 7, 2005·Blood Pressure Monitoring·Paolo Verdecchia, Fabio Angeli
Feb 24, 2006·Blood Pressure Monitoring·Fabio AngeliGianpaolo Reboldi
Jul 1, 2006·Blood Pressure Monitoring·Dogan ErdoganHaldun Muderrisoglu
Aug 26, 2006·Blood Pressure Monitoring·Daniele LongoPaolo Palatini
Sep 19, 2008·Blood Pressure Monitoring·Gregory VyssoulisChristodoulos Stefanadis
Mar 1, 2008·Clinical and Experimental Pharmacology & Physiology·Catherine MartinBarry McGrath
Oct 30, 1998·Fundamental & Clinical Pharmacology·P Lantelme, H Milon
Dec 21, 2004·International Journal of Clinical Practice·E CobanC Ermiş
Feb 24, 2000·Archives of Disease in Childhood·C D Goonasekera, M J Dillon
Jan 3, 2006·Heart·D ErdoganH Muderrisoglu
Jul 24, 2002·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Masanori MunakataKaoru Yoshinaga
Mar 24, 2005·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Takao NakashimaYoshihiko Saito
Jun 17, 2006·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Osamu TochikuboKiyoko Nishijima
Apr 27, 2007·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Satoshi HoshideKazuomi Kario
Oct 2, 2012·Clinical Journal of the American Society of Nephrology : CJASN·Paolo PalatiniUNKNOWN HARVEST Investigators
Mar 7, 2014·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Anastasios KolliasGeorge S Stergiou
Jun 14, 2001·Journal of Hypertension·P VerdecchiaA C Pessina
Jun 29, 2000·Journal of Hypertension·T T Rosa, P Palatini
Feb 10, 2006·Journal of Hypertension·Cesare Cuspidi, Gianfranco Parati
Apr 14, 2006·Journal of Hypertension·Christoph D Gatzka
Jan 11, 2012·Blood Pressure·Aytekin GuvenHaldun Muderrisoglu
Dec 8, 2004·Blood Pressure·Paolo Verdecchia, Gian Paolo Reboldi
Mar 10, 2004·Chest·Francisco García-RíoJosé Villamor
Oct 13, 2009·Medicina clínica·Daniel Sabater-HernándezMaría José Faus
Jan 7, 2016·Journal of Hypertension·Alexandros BriasoulisDimitris Tousoulis

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