Target volume definition in radiation therapy

The British Journal of Radiology
M Van KampenM Wannenmacher

Abstract

Target volume definition in radiation therapy is a broad field of interdisciplinary research. We give a brief history of clinical research in this field and outline some remarkable steps which led to the well-defined target volume concepts. The challenges in target volume definition for high-precision conformal radiation therapy are discussed, and possibilities of improving target volume definition, such as the integration of modern imaging modalities and the use of computer-based systems to support the radiation oncologist are indicated, as well as novel techniques for increasing the accuracy of patient positioning. All these tools should be evaluated with regard to their potential for increasing the therapeutic ratio and, as appropriate, should be implemented in clinical practice. However, target volume definition is a complex process influenced by many factors, currently under investigation. While questions remain in this field, and the impact of the influencing factors is not defined, the process of target volume definition should remain the subject of clinical research.

References

Oct 11, 1992·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·R K Ten HakenD L McShan
Jan 11, 1992·International Journal of Radiation Oncology, Biology, Physics·A F ThorntonB R Yanke
Jan 1, 1992·International Journal of Radiation Oncology, Biology, Physics·L E ReinsteinA G Meek
Dec 1, 1991·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·C WestbrookJ Yarnold
Dec 1, 1991·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·G van TienhovenB J Mijnheer
Jul 1, 1991·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·C MitineE van der Schueren
May 15, 1991·International Journal of Radiation Oncology, Biology, Physics·B EmamiM Wesson
Mar 1, 1990·International Journal of Radiation Oncology, Biology, Physics·C S RossJ F Doornbos
Aug 1, 1989·International Journal of Radiation Oncology, Biology, Physics·A LusinchiF Eschwege
Sep 1, 1989·International Journal of Radiation Oncology, Biology, Physics·J E MunzenriderP McManus
Feb 1, 1989·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·J C Flickinger, M Deutsch
Jun 1, 1987·Journal of Neurosurgery·P J KellyJ J Illig
Apr 1, 1988·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·R B KeusJ P Bataini
Feb 1, 1988·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·H HuizengaA G Visser
Aug 1, 1983·International Journal of Radiation Oncology, Biology, Physics·S A LeibelT L Phillips
Dec 1, 1995·International Journal of Radiation Oncology, Biology, Physics·F E YangS Vijayakumar
Oct 1, 1994·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·V RudatM Wannenmacher
Mar 1, 1994·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·V LiengswangwongJ Q Su
Oct 20, 1993·International Journal of Radiation Oncology, Biology, Physics·J M MichalskiC A Perez
Aug 1, 1993·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·J F Valley, R O Mirimanoff
Oct 1, 1993·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·C WeltensE van der Schueren
Nov 1, 1993·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·G LeunensE van der Schueren
Feb 15, 1993·International Journal of Radiation Oncology, Biology, Physics·J P AustinJ E Munzenrider
Apr 30, 1993·International Journal of Radiation Oncology, Biology, Physics·P B DunscombeK Leszczynski
Nov 1, 1995·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M NiewaldU Humke
Jun 1, 1996·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·B MageeS S Banerjee
Feb 29, 1996·European Journal of Pharmacology·J Van KampenA J Stoessl
Jan 15, 1997·International Journal of Radiation Oncology, Biology, Physics·J LaverdièreF Labrie
Jan 15, 1997·International Journal of Radiation Oncology, Biology, Physics·C H KettingJ Jacky
Feb 1, 1997·International Journal of Radiation Oncology, Biology, Physics·C H KettingT Griffin
Jan 1, 1997·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·V S KhooM O Leach

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Citations

Sep 18, 2013·Journal of Digital Imaging·Jayashree Kalpathy-CramerClifton D Fuller
Aug 23, 2001·International Journal of Radiation Oncology, Biology, Physics·M van KampenM Wannenmacher
Aug 21, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Stefan RiekenStephanie E Combs
Feb 5, 2008·Seminars in Nuclear Medicine·Jacqueline BrunettiCharles Vialotti

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