PMID: 22202152Dec 29, 2011

Targeted alpha therapy with 213Bi

Current Radiopharmaceuticals
A MorgensternC Apostolidis

Abstract

The potential of targeted therapy with the alpha emitter 213Bi has been successfully demonstrated in a large number of preclinical studies and several clinical trials have provided evidence for its feasibility, safety and therapeutic efficacy. This review describes methods for the production of 225Ac and 225Ac/213Bi radionuclide generators, gives an overview of selected preclinical studies and summarizes the current clinical experience with 213Bi.

Citations

Feb 19, 2013·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·M MarouliA Morgenstern
Mar 21, 2013·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·G SulimanA Morgenstern
Jan 1, 2014·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·G WangA G Denkova
May 13, 2014·Immunotherapy·Christof Seidl
Sep 25, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Donal M Keogan, Darren M Griffith
Nov 3, 2012·Nuclear Medicine and Biology·Tapas Das, M R A Pillai
Sep 4, 2012·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·S PomméA Morgenstern
Apr 3, 2012·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·S PomméA Morgenstern
Feb 10, 2018·Targeted Oncology·Mehran MakvandiJeffrey P Norenberg
Nov 17, 2017·Journal of Labelled Compounds & Radiopharmaceuticals·Johannes Notni, Hans-Jürgen Wester
Feb 2, 2019·Current Topics in Medicinal Chemistry·Wei DiaoZhiyun Jia
Mar 24, 2020·Cancer Biotherapy & Radiopharmaceuticals·Hossein Jadvar
Feb 15, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Licia UccelliAlessandra Boschi
Nov 30, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Narges K TafreshiDavid L Morse
Oct 4, 2017·Current Medicinal Chemistry·Mateusz KowalikBarbara Barszcz
Oct 21, 2020·Dalton Transactions : an International Journal of Inorganic Chemistry·Jaclyn L LangeBrett M Paterson

Related Concepts

Alpha Radiation
Bismuth
Isotope Labeling, Stable
Malignant Neoplasms
Radioisotopes
Radiopharmaceuticals
Clinical Trials
Experience
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