Targeted MRI/TRUS fusion-guided biopsy in men with previous prostate biopsies using a novel registration software and multiparametric MRI PI-RADS scores: first results

World Journal of Urology
Susanne TewesInga Peters

Abstract

To evaluate a novel system for MRI/TRUS fusion-guided biopsy for detection of prostate cancer (PCa) in patients with previous negative prostate biopsy and determine diagnostic accuracy when using the Prostate Imaging Reporting and Data System (PI-RADS) for multiparametric magnetic resonance imaging (mpMRI) as proposed by the European Society of Urogenital Radiology. Thirty-nine men with clinical suspicion of PCa and history of previous prostate biopsy underwent mpMRI on a 3-T MRI. In total, 72 lesions were evaluated by the consensus of two radiologists. PI-RADS scores for each MRI sequence, the sum of the PI-RADS scores and the global PI-RADS were determined. MRI/TRUS fusion-guided targeted biopsy was performed using the BioJet™ software combined with a transrectal ultrasound system. Image fusion was based on rigid registration. PI-RADS scores of the dominant lesion were compared with histopathological results. Diagnostic accuracy was determined using receiver operating characteristic curve analysis. MRI/TRUS fusion-guided biopsy was reliable and successful for 71 out of 72 lesions. The global PI-RADS score of the dominant lesion was significantly higher in patients with PCa (4.0 ± 1.3) compared to patients with negative histop...Continue Reading

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Citations

Jul 2, 2015·World Journal of Urology·Daniel JunkerUNKNOWN Training Research in Urological Surgery Therapy (T.R.U.S.T.) group
Jul 9, 2016·Journal of Magnetic Resonance Imaging : JMRI·Matthew D GreerBaris Turkbey
Jun 4, 2020·Therapeutic Advances in Urology·Andrea BenelliAndrea Gregori
Jun 27, 2018·World Journal of Urology·Christopher WarlickBadrinath R Konety
May 23, 2018·World Journal of Urology·Samuel A GoldPeter A Pinto
Oct 14, 2020·The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS·Jose D Velazco-GarciaNikolaos V Tsekos

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