Targeted NIR-II emissive nanoprobes for tumor detection in mice and rabbits.

Chemical Communications : Chem Comm
Yaxi LiKai Li

Abstract

The functional NIR-II emissive nanoprobe loaded with AIEgen (cRGD-TTB NPs) achieved a high quantum yield (10.32%) and a high signal-to-background (S/B) ratio of 7.7 when employed for the visualization of large tumors (∼600 mm3) in rabbit models for the first time. This work will aid in the investigation of tumor targeting effect of therapeutic agents in large animal models.

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Citations

Sep 15, 2021·Advanced Healthcare Materials·Menglei ZhaKai Li
Dec 3, 2021·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Yaxi LiKai Li

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