Targeted therapies: a nursing perspective

Seminars in Oncology Nursing
Polly Kay

Abstract

To review the development of targeted therapies and the biology of relevant therapeutic targets. To analyze the relevance of targeted agents as part of current clinical practice. Research articles. Several targeted agents are now available for clinical use. Their mechanisms of action are more specific against tumor cells than traditional cytotoxics. Monotherapy regimens based on targeted agents tend to be better tolerated than chemotherapy, and most combination regimens with targeted agents have proven feasible. Their availability has greatly expanded cancer treatment options, especially for chemorefractory patients. Nurses involved in the care of patients with cancer can benefit from an increased understanding of targeted therapies, including their mechanisms of action, their efficacy profile, as well as prophylaxis and management of adverse events and administration procedures.

References

Jul 1, 1995·Critical Reviews in Oncology/hematology·D S SalomonN Normanno
Apr 2, 2004·Expert Review of Anticancer Therapy·Robert Z Orlowski
Jun 26, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Ramaswamy Govindan
Feb 24, 2005·Seminars in Oncology·Timothy S Collins, Herbert I Hurwitz

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Citations

Feb 17, 2009·Seminars in Oncology Nursing·Kathleen K Reed, Rita Wickham

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