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Targeting DNA with small molecules: a comparative study of a library of azonia aromatic chromophores

Organic & Biomolecular Chemistry

Jan 14, 2015

Rosa M SuárezJuan José Vaquero

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Abstract

A library of azonia aromatic cations has been studied in order to gain insights into the effect of the size, shape and charge distribution on the fluorescence, DNA interactions and DNA sequence selectivity properties. Fluorescence-based thermal denaturation experiments, spectrofluorimet...read more

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  • Targeting DNA with small molecules: a comparative study of a library of azonia aromatic chromophores

    Organic & Biomolecular Chemistry

    Jan 14, 2015

    Rosa M SuárezJuan José Vaquero

    PMID: 25378061

    DOI: 10.1039/c4ob01465k

    Abstract

    A library of azonia aromatic cations has been studied in order to gain insights into the effect of the size, shape and charge distribution on the fluorescence, DNA interactions and DNA sequence selectivity properties. Fluorescence-based thermal denaturation experiments, spectrofluorimet...read more

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