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Targeting of Mycobacterium tuberculosis heparin-binding hemagglutinin to mitochondria in macrophages

PLoS Pathogens

Dec 17, 2011

Hosung SohnHwa-Jung Kim

Abstract

Mycobacterium tuberculosis heparin-binding hemagglutinin (HBHA), a virulence factor involved in extrapulmonary dissemination and a strong diagnostic antigen against tuberculosis, is both surface-associated and secreted. The role of HBHA in macrophages during M. tuberculosis infection, h...read more

Mentioned in this Paper

Pathologic Cytolysis
Caspase-9
Establishment and Maintenance of Localization
Mitochondrial Toxicity
Pathogenic Aspects
Flow Cytometry
Biochemical Pathway
Amidophosphoribosyltransferase
HbhA protein, Mycobacterium tuberculosis
Necrosis
Paper Details
References
  • References44
  • Citations18
12

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Targeting of Mycobacterium tuberculosis heparin-binding hemagglutinin to mitochondria in macrophages

PLoS Pathogens

Dec 17, 2011

Hosung SohnHwa-Jung Kim

PMID: 22174691

DOI: 10.1371/journal.ppat.1002435

Abstract

Mycobacterium tuberculosis heparin-binding hemagglutinin (HBHA), a virulence factor involved in extrapulmonary dissemination and a strong diagnostic antigen against tuberculosis, is both surface-associated and secreted. The role of HBHA in macrophages during M. tuberculosis infection, h...read more

Mentioned in this Paper

Pathologic Cytolysis
Caspase-9
Establishment and Maintenance of Localization
Mitochondrial Toxicity
Pathogenic Aspects
Flow Cytometry
Biochemical Pathway
Amidophosphoribosyltransferase
HbhA protein, Mycobacterium tuberculosis
Necrosis

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References44
  • Citations18
12
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