TASH: Toolbox for the Automated Segmentation of Heschl's gyrus.

Scientific Reports
Josué Luiz Dalboni da RochaNarly Golestani

Abstract

Auditory cortex volume and shape differences have been observed in the context of phonetic learning, musicianship and dyslexia. Heschl's gyrus, which includes primary auditory cortex, displays large anatomical variability across individuals and hemispheres. Given this variability, manual labelling is the gold standard for segmenting HG, but is time consuming and error prone. Our novel toolbox, called 'Toolbox for the Automated Segmentation of HG' or TASH, automatically segments HG in brain structural MRI data, and extracts measures including its volume, surface area and cortical thickness. TASH builds upon FreeSurfer, which provides an initial segmentation of auditory regions, and implements further steps to perform finer auditory cortex delineation. We validate TASH by showing significant relationships between HG volumes obtained using manual labelling and using TASH, in three independent datasets acquired on different scanners and field strengths, and by showing good qualitative segmentation. We also present two applications of TASH, demonstrating replication and extension of previously published findings of relationships between HG volumes and (a) phonetic learning, and (b) musicianship. In sum, TASH effectively segments HG ...Continue Reading

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Citations

Nov 13, 2020·The European Journal of Neuroscience·Lutz JänckeSusan Merillat

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Software Mentioned

MATLAB
Tim
Symphony
TCSH scripts
freeview
Trio
SANLM
TASH
VBM
CAT

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