Task complexity enhances response inhibition deficits in childhood and adolescent attention-deficit/hyperactivity disorder: a meta-regression analysis

Biological Psychiatry
Hilde M HuizengaMaurits W van der Molen

Abstract

The ability to inhibit motor responses, as assessed by the stop-signal reaction time (SSRT), is impaired in children and adolescents with attention-deficit/hyperactivity disorder (ADHD). However, the between-study variation in effect sizes is large. The aim of this study was to investigate whether this variability can be explained by between-study variation in Go task complexity. Forty-one studies comparing children or adolescents diagnosed with ADHD to normal control subjects were incorporated in a random-effects meta-regression analysis. The independent variables were a global index of Go task complexity (i.e., mean reaction time in control subjects [RTc]) and a more specific index (i.e., spatial compatibility of the stimulus-response mapping). The dependent variable was the SSRT difference between ADHD and control subjects. The SSRT difference increased significantly with increasing RTc. Moreover, the SSRT difference was significantly increased in studies that employed a noncompatible, that is, arbitrary, mapping compared with studies that incorporated a spatially compatible stimulus-response mapping. These results indicate that inhibitory dysfunction in children and adolescents with ADHD varies with task complexity: inhibit...Continue Reading

References

Aug 1, 1995·Journal of Abnormal Child Psychology·R SchacharG Logan
Feb 1, 1996·Journal of Abnormal Child Psychology·J Oosterlaan, J A Sergeant
Aug 1, 1997·Journal of Developmental and Behavioral Pediatrics : JDBP·S R PliszkaS Irick
Aug 26, 1998·Behavioural Brain Research·K RubiaT v Leeuwen
Mar 10, 1999·Statistics in Medicine·S L Normand
Apr 13, 2000·Journal of the American Academy of Child and Adolescent Psychiatry·K L Purvis, R Tannock
Sep 15, 2000·Journal of the American Academy of Child and Adolescent Psychiatry·K ManassisJ Barbosa
Mar 31, 2001·Journal of Child Psychology and Psychiatry, and Allied Disciplines·J KuntsiJ Stevenson
Apr 6, 2001·Journal of the American Academy of Child and Adolescent Psychiatry·M SlusarekC Eggers
Apr 26, 2001·Journal of Child Psychology and Psychiatry, and Allied Disciplines·A ScheresJ A Sergeant
Aug 3, 2001·The British Journal of Psychiatry : the Journal of Mental Science·K RubiaH Oksannen
Feb 12, 2002·Statistics in Medicine·Hans C van HouwelingenTheo Stijnen
May 7, 2002·Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence·K KonradM Schöll
Aug 3, 2002·Nature Reviews. Neuroscience·F Xavier Castellanos, Rosemary Tannock
Nov 29, 2002·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Julia J Rucklidge, Rosemary Tannock
Jan 11, 2003·Acta Psychologica·Guido P H BandGordon D Logan
Feb 18, 2003·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Eveline A CroneMaurits W van der Molen
Jun 20, 2003·Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence·Robert J McInerney, Kimberly A Kerns
Dec 11, 2003·Psychological Methods·Charles F BondF Dan Richard
Feb 20, 2004·Journal of Experimental Child Psychology·Wery P M van den Wildenberg, Maurits W van der Molen
Mar 31, 2004·Trends in Cognitive Sciences·Adam R AronRussell A Poldrack
Apr 2, 2004·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Hilde M GeurtsJoseph A Sergeant
Jul 2, 2004·Journal of Abnormal Child Psychology·Russell J SchacharAmber Pakulak
Oct 23, 2004·Journal of Clinical Child and Adolescent Psychology : the Official Journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53·Christy Mangione Walcott, Steven Landau
Mar 23, 2005·Journal of the American Academy of Child and Adolescent Psychiatry·Rhonda MartinussenRosemary Tannock
Jun 3, 2005·The American Journal of Psychiatry·Katya RubiaEric Taylor
Jul 5, 2005·Acta Psychologica·Frederick VerbruggenAndré Vandierendonck
Feb 18, 2006·Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence·Giorgio P Fuggetta
Mar 4, 2006·Journal of Cognitive Neuroscience·Christopher D ChambersJason B Mattingley
Nov 11, 2006·The Quarterly Journal of Experimental Psychology : QJEP·Sharon Morein-ZamirAlan Kingstone
Mar 14, 2007·Journal of Abnormal Child Psychology·Russell SchacharCathy Barr
Apr 25, 2007·Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence·Katya RubiaEric Taylor
Jul 3, 2007·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Stuart J JohnstoneAdam R Clarke
Aug 2, 2007·Journal of Abnormal Child Psychology·R Matt AldersonMichael J Kofler
Oct 19, 2007·Journal of Neurophysiology·Christopher D ChambersJason B Mattingley

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Citations

Apr 2, 2013·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·A PasiniA Pizzuti
Oct 28, 2009·The Clinical Neuropsychologist·Nicholas S ThalerJoan Mayfield
Sep 11, 2010·Environmental Health Perspectives·Andréa AguiarSusan L Schantz
Aug 14, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jeng-Ren DuannChiang-shan Ray Li
Mar 16, 2016·Clinical Psychology Review·Tycho J DekkersHilde M Huizenga
Jan 30, 2016·The Quarterly Journal of Experimental Psychology : QJEP·Kathrin WeidackerStephen J Johnston
Aug 2, 2013·Journal of Intellectual Disability Research : JIDR·A BexkensH M Huizenga
Oct 26, 2010·Journal of the American Academy of Child and Adolescent Psychiatry·Denis G SukhodolskyRobert T Schultz
Dec 17, 2009·Behavioral and Brain Functions : BBF·Anne H UdalBerit Groholt
Oct 21, 2016·Experimental Brain Research·Mikael CavalletLuiz G Gawryszewski
Nov 28, 2013·Journal of Attention Disorders·Kjell Tore HovikMerete Øie
Sep 19, 2018·Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence·Stephanie J TarleDelanie K Roberts
May 26, 2017·European Child & Adolescent Psychiatry·Tycho J DekkersHilde M Huizenga

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