Task Failure during Exercise to Exhaustion in Normoxia and Hypoxia Is Due to Reduced Muscle Activation Caused by Central Mechanisms While Muscle Metaboreflex Does Not Limit Performance

Frontiers in Physiology
Rafael Torres-PeraltaJosé A L Calbet

Abstract

To determine whether task failure during incremental exercise to exhaustion (IE) is principally due to reduced neural drive and increased metaboreflex activation eleven men (22 ± 2 years) performed a 10 s control isokinetic sprint (IS; 80 rpm) after a short warm-up. This was immediately followed by an IE in normoxia (Nx, PIO2:143 mmHg) and hypoxia (Hyp, PIO2:73 mmHg) in random order, separated by a 120 min resting period. At exhaustion, the circulation of both legs was occluded instantaneously (300 mmHg) during 10 or 60 s to impede recovery and increase metaboreflex activation. This was immediately followed by an IS with open circulation. Electromyographic recordings were obtained from the vastus medialis and lateralis. Muscle biopsies and blood gases were obtained in separate experiments. During the last 10 s of the IE, pulmonary ventilation, VO2, power output and muscle activation were lower in hypoxia than in normoxia, while pedaling rate was similar. Compared to the control sprint, performance (IS-Wpeak) was reduced to a greater extent after the IE-Nx (11% lower P < 0.05) than IE-Hyp. The root mean square (EMGRMS) was reduced by 38 and 27% during IS performed after IE-Nx and IE-Hyp, respectively (Nx vs. Hyp: P < 0.05). Post...Continue Reading

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Citations

May 23, 2017·Motor Control·Jerónimo Aragón-VelaJesús F Rodríguez Huertas
Sep 24, 2016·Journal of Applied Physiology·Daniel T CannonHarry B Rossiter
Jul 7, 2020·Acta Physiologica·Callum G BrownsteinKevin Thomas
Mar 23, 2019·International Journal of Environmental Research and Public Health·On-Kei LeiJinlei Nie
Feb 12, 2017·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·David CurtelinJosé Al Calbet
Jun 2, 2020·Frontiers in Physiology·Christian FroydTimothy D Noakes
Dec 22, 2016·Frontiers in Psychology·Guy Cheron
Oct 6, 2020·Frontiers in Physiology·Marcos Martin-Rincon, Jose A L Calbet
Sep 25, 2021·International Journal of Sports Physiology and Performance·Fernando G BeltramiTimothy D Noakes

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