Task load modulates tDCS effects on brain network for phonological processing

Cognitive Processing
Lílian Rodrigues de AlmeidaPeter C. Hansen

Abstract

Motor participation in phonological processing can be modulated by task nature across the speech perception to speech production range. The pars opercularis of the left inferior frontal gyrus (LIFG) would be increasingly active across this range, because of changing motor demands. Here, we investigated with simultaneous tDCS and fMRI whether the task load modulation of tDCS effects translates into predictable patterns of functional connectivity. Findings were analysed under the "multi-node framework", according to which task load and the network structure underlying cognitive functions are modulators of tDCS effects. In a within-subject study, participants (N = 20) performed categorical perception, lexical decision and word naming tasks [which differentially recruit the target of stimulation (LIFG)], which were repeatedly administered in three tDCS sessions (anodal, cathodal and sham). The LIFG, left superior temporal gyrus and their right homologues formed the target network subserving phonological processing. C-tDCS inhibition and A-tDCS excitation should increase with task load. Correspondingly, the larger the task load, the larger the relevance of the target for the task and smaller the room for compensation of C-tDCS inhib...Continue Reading

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Citations

Jun 25, 2021·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Sabrina Turker, Gesa Hartwigsen

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Software Mentioned

MCFLIRT
PPCOR R package
FSL Featquery
FSL FEAT
Neurosynth
AROMA
VWR R
nlme
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SUBTLEXus

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