Tasmanian devil facial tumour disease: lessons for conservation biology

Trends in Ecology & Evolution
Hamish McCallum

Abstract

Tasmanian devil facial tumour disease is an infectious cancer that threatens the largest surviving marsupial carnivore with extinction. After emerging in 1996, it has spread across most of the range of the species, leading to a population decline of more than 60%. This bizarre disease, in which the cancer cells themselves are the infective agent, illustrates some important general principles about disease and conservation biology, including the threat posed by loss of genetic diversity and the potential of pathogens with frequency-dependent transmission to cause extinction.

References

Mar 1, 1979·Journal of the National Cancer Institute·L A Griner
Aug 2, 1979·Nature·R M Anderson, R M May
Aug 9, 1979·Nature·R M May, R M Anderson
Mar 22, 1985·Science·S J O'BrienD E Wildt
Jul 1, 1988·Journal of Wildlife Diseases·E S WilliamsD W Belitsky
Feb 1, 1996·Nature·M E Roelke-ParkerM J Appel
Jul 22, 1998·Proceedings of the National Academy of Sciences of the United States of America·L BergerH Parkes
Jun 17, 1999·Trends in Ecology & Evolution·P Daszak, A A Cunningham
Sep 11, 1999·Trends in Ecology & Evolution·P A Stephens, W J Sutherland
Apr 18, 2001·Veterinary Research Communications·U Das, A K Das
May 23, 2001·Trends in Ecology & Evolution·H McCallumJ Hone
Apr 27, 2002·Revue Scientifique Et Technique·G Wobeser
Jan 14, 2003·Revue Scientifique Et Technique·G K BrücknerM E Mogajane
Oct 16, 2003·Biological Reviews of the Cambridge Philosophical Society·Franck CourchampMichel Pascal
Aug 12, 2005·Heredity·S B Piertney, M K Oliver
Feb 17, 2006·Proceedings of the National Academy of Sciences of the United States of America·Karen R LipsJames P Collins
May 17, 2006·Trends in Ecology & Evolution·James O Lloyd-SmithAndrea Swei
Jun 13, 2006·Trends in Ecology & Evolution·Karina Acevedo-Whitehouse, Andrew A Cunningham
Aug 12, 2006·Cell·Claudio MurgiaRobin A Weiss
Sep 28, 2006·Conservation Biology : the Journal of the Society for Conservation Biology·Katherine F SmithKevin D Lafferty
Oct 20, 2006·PLoS Biology·Hamish McCallum, Menna Jones
Mar 16, 2007·Proceedings. Biological Sciences·Pälvi SaloChris R Dickman
Mar 30, 2007·Conservation Biology : the Journal of the Society for Conservation Biology·Jason S McLachlanMark W Schwartz
Jul 20, 2007·Current Biology : CB·David M Hillis
Aug 24, 2007·The Journal of Animal Ecology·Shelly LachishHamish McCallum
Oct 4, 2007·Proceedings of the National Academy of Sciences of the United States of America·Hannah V SiddleKatherine Belov
Feb 26, 2008·Conservation Biology : the Journal of the Society for Conservation Biology·Steven R EwingLukas F Keller
Jul 16, 2008·Proceedings of the National Academy of Sciences of the United States of America·Menna E JonesDavid Pemberton
Oct 1, 1988·Trends in Ecology & Evolution·S J O'Brien, J F Evermann
May 1, 1995·Trends in Ecology & Evolution·H McCallum, A Dobson

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Citations

May 8, 2013·Proceedings of the National Academy of Sciences of the United States of America·Erica Bree RosenblumJason E Stajich
Jun 5, 2012·Annual Review of Genomics and Human Genetics·Janine E Deakin, Katherine Belov
Dec 25, 2009·Cancer Immunology, Immunotherapy : CII·Ariberto Fassati, N Avrion Mitchison
Sep 29, 2011·International Journal of Molecular Sciences·Beata Ujvari, Katherine Belov
May 9, 2012·BMC Genomics·Maria A NilssonBjörn M Hallström
Oct 22, 2010·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Katherine Belov
Sep 12, 2012·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Hamish McCallum
Nov 9, 2012·Proceedings. Biological Sciences·Beata UjvariKatherine Belov
Apr 7, 2015·Epidemics·Mick RobertsLorenzo Pellis
Jul 30, 2010·Ecological Applications : a Publication of the Ecological Society of America·Eve McDonald-MaddenBrendan A Wintle
Jun 19, 2012·Molecular Phylogenetics and Evolution·Johanna L A PaijmansMichael Hofreiter
Jun 15, 2011·European Journal of Cell Biology·Barbara Uchanska-ZieglerAndreas Ziegler
Sep 29, 2009·Trends in Ecology & Evolution·Pablo M Beldomenico, Michael Begon
Oct 8, 2011·Conservation Biology : the Journal of the Society for Conservation Biology·Rodrigo HamedeHamish McCallum
Feb 1, 2012·Molecular Ecology·Eric Vander WalJosé A Andrés
Jan 26, 2013·The Journal of Animal Ecology·Thomas A A ProwseBarry W Brook
Apr 13, 2011·Conservation Biology : the Journal of the Society for Conservation Biology·Howard B WilsonHugh P Possingham
Mar 3, 2012·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Katherine Belov
Aug 26, 2010·The Journal of Animal Ecology·Daniel M TompkinsSandra Telfer
May 18, 2010·International Journal of Cancer. Journal International Du Cancer·Iain D O'Neill
Feb 27, 2013·Anatomia, histologia, embryologia·K HayashiS Abe
Dec 4, 2014·Evolutionary Applications·Eric Vander WalFanie Pelletier
Feb 26, 2014·Evolutionary Applications·Beata UjvariThomas Madsen
Apr 15, 2016·PeerJ·Miguel Baltazar-SoaresChristophe Eizaguirre
Jun 2, 2015·Trends in Genetics : TIG·Catherine E GrueberKatherine Belov
Aug 19, 2015·Parasitology·Hamish McCALLUM
Nov 11, 2014·Annual Review of Animal Biosciences·Hannah S BenderJanine E Deakin
Aug 8, 2014·Environmental Science & Technology·Adélaïde LereboursJeanette M Rotchell
Oct 29, 2017·Conservation Biology : the Journal of the Society for Conservation Biology·Holly R CopeCatherine A Herbert
Jun 25, 2009·Nature Reviews. Cancer·Denise McAloose, Alisa L Newton

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