Abstract
Taste (rasa) is traditionally valued in Ayurveda as an important ethnopharmacological category, and reported to correlate with certain therapeutic activities (karman). The present paper endeavors to provide for the first time a type of mapping of ayurvedic ethnopharmacological space by the integration of medicinal plant taste-activity relationship (TA) data, originating from several traditional sources. The present TA database included 183 ayurvedic medicinal plants, with their traditional description of taste and ethnophamacological actions (EPA). 111 plants had a unique taste, and 72 plants a combination of several tastes, consisting of one principal taste, and other 2-4 secondary tastes. 121 ethnopharmacological actions were considered. Potential global or individual associations between rasa and karman were statistically analyzed. We found a statistically significant global correspondence between the predominant plant taste and the ethnopharmacological activities (Chi-square test, p<0.05), and the following individual associations (Fisher exact test, p<0.05, positive association if lnOR >0, negative association if lnOR <0): bitter- 11 positive associations (lnOR 0.940 to 3.544) and 8 negative associations (lnOR -0.997 to -3...Continue Reading
References
Jan 1, 1989·The American Journal of Chinese Medicine·S Mahdihassan
Jan 1, 1982·Physiology & Behavior·R P Erickson
Oct 1, 1980·Physiology & Behavior·R P Erickson, E Covey
Sep 2, 2005·Nature·Gary K BeauchampPaul A S Breslin
Jul 15, 2006·Nature Biotechnology·Gaia V PaoliniAndrew L Hopkins
Oct 22, 2008·Nature Chemical Biology·Andrew L Hopkins
Jul 10, 2009·Frontiers in Integrative Neuroscience·Xueying RenIvan E de Araujo
Jan 1, 2010·Journal of Ayurveda and Integrative Medicine·Padma VenkatasubramanianVenugopalan S N Nair
Sep 24, 2011·Nucleic Acids Research·Ayana WienerMasha Y Niv
Jul 28, 2012·Brain Research·Ozra DehkordiAnnapurni Jayam-Trouth
Aug 31, 2012·Science Signaling·Jean-Claude Henquin
Sep 12, 2012·Seminars in Cell & Developmental Biology·Kurumi Yamamoto, Yoshiro Ishimaru
Feb 21, 2013·Molecular Human Reproduction·Feng Li
Aug 28, 2014·Journal of Ethnobiology and Ethnomedicine·Soledad Molares, Ana Ladio
Dec 3, 2014·Journal of Ethnopharmacology·Patrícia Muniz de MedeirosViviany Teixeira do Nascimento
Jan 17, 2015·Ancient Science of Life·Sudipta Kumar RathAshashri Shinde
Citations
Jun 11, 2016·Journal of Ethnopharmacology·François ChassagneGeneviève Bourdy
Jan 11, 2018·International Journal of Molecular Sciences·Xu ZhangGongyu Li
Nov 14, 2017·IUBMB Life·Ido NissimMasha Y Niv
Jun 24, 2017·Evidence-based Complementary and Alternative Medicine : ECAM·Marilena Gilca, Dorin Dragos
Aug 6, 2019·Frontiers in Physiology·Mingzhi LuoLinhong Deng
Aug 24, 2021·Chemical & Pharmaceutical Bulletin·Guoliang BaiXin Ni