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Tau PET imaging with 18 F-PI-2620 in patients with Alzheimer's disease and healthy controls: a first-in-human study

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine

Nov 11, 2019

Andre MuellerAndrew W Stephens

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Abstract

18F-PI-2620 is a positron emission tomography (PET) tracer with high binding affinity for aggregated tau, a key pathologic feature of Alzheimer's disease (AD) and other neurodegenerative disorders. Preclinically, 18F-PI-2620 binds to both, 3R and 4R tau isoforms. The purpose of this fir...read more

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Almitrine Dimesylate
Alzheimer's Disease
Brain Diseases
Diagnostic Imaging
Parietal Lobe
Positron-Emission Tomography
Research Subject
Tau Proteins
Human Study
Dorsal
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Tau PET imaging with 18 F-PI-2620 in patients with Alzheimer's disease and healthy controls: a first-in-human study

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine

Nov 11, 2019

Andre MuellerAndrew W Stephens

PMID: 31712323

DOI: 10.2967/jnumed.119.236224

Abstract

18F-PI-2620 is a positron emission tomography (PET) tracer with high binding affinity for aggregated tau, a key pathologic feature of Alzheimer's disease (AD) and other neurodegenerative disorders. Preclinically, 18F-PI-2620 binds to both, 3R and 4R tau isoforms. The purpose of this fir...read more

Mentioned in this Paper

Almitrine Dimesylate
Alzheimer's Disease
Brain Diseases
Diagnostic Imaging
Parietal Lobe
1
1

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