Taurine-sulfur assimilation and taurine-pyruvate aminotransferase activity in anaerobic bacteria.

Applied and Environmental Microbiology
C ChienW Godchaux

Abstract

We demonstrated the ability of strictly fermentative, as well as facultatively fermentative, bacteria to assimilate sulfonate sulfur for growth. Taurine (2-aminoethanesulfonate) can be utilized by Clostridium pasteurianum C1 but does not support fermentative growth of two Klebsiella spp. and two different Clostridium spp. However, the latter are able to assimilate the sulfur of a variety of other sulfonates (e.g., cysteate, 3-sulfopyruvate, and 3-sulfolactate) anaerobically. A novel taurine-pyruvate aminotransferase activity was detected in cell extracts of C. pasteurianum C1 grown with taurine as the sole sulfur source. This activity was not detected in extracts of other bacteria examined, in C. pasteurianum C1 grown with sulfate or sulfite as the sulfur source, or in a Klebsiella isolate assimilating taurine-sulfur by aerobic respiration. More common aminotransferase activities (e.g., with aspartate or glutamate as the amino donor and pyruvate, oxalacetate, or (alpha)-ketoglutarate as the amino acceptor) were present, no matter what sulfur source was used for growth. Partial characterization of the taurine-pyruvate aminotransferase revealed an optimal temperature of 37(deg)C and a broad optimal pH range of 7.5 to 9.5.

References

Aug 15, 1979·Biochimica Et Biophysica Acta·G Shimamoto, R S Berk
Jan 1, 1992·Physiological Reviews·R J Huxtable
Jul 1, 1987·Applied and Environmental Microbiology·D ZürrerT Leisinger
Apr 1, 1968·Physiological Reviews·J G Jacobsen, L H Smith
Feb 16, 1972·Biochemical and Biophysical Research Communications·S ToyamaK Soda
Nov 1, 1994·Biochemical Society Transactions·D P KellyG A Dubinina
Feb 1, 1993·Journal of General Microbiology·M R Uria-NickelsenW Godchaux
Nov 1, 1952·Nature·S DARLING
Feb 1, 1957·Journal of Cellular Physiology·G COHEN-BAZIRER Y STANIER
Oct 1, 1963·Journal of Biochemistry·K IKEDAS TANAKA
Jan 1, 1965·Applied Microbiology·M A BenardeL Shaulis
Feb 1, 1954·Proceedings of the National Academy of Sciences of the United States of America·B A Koechlin

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Citations

Feb 17, 1999·FEMS Microbiology Reviews·A M CookF Junker
Jul 28, 2019·The Biochemical Journal·Meining XingYan Zhang
Apr 8, 2021·Annual Review of Biochemistry·Yifeng Wei, Yan Zhang

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