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Taurolidine-citrate lock solution for prevention of endoluminal central venous catheter infection in neutropenic hematological patients: a randomized, double-blind, placebo-controlled trial (TAURCAT)

Antimicrobial Agents and Chemotherapy

Nov 11, 2019

Carlota GudiolJordi Carratalà

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Abstract

Background: Infection of long-term central venous catheters (CVCs) remains a challenge in the clinical management of cancer patients. We aimed to determine whether a lock solution with taurolidine-citrate-heparin would be more effective than placebo for preventing non-tunnelled CVC infe...read more

Mentioned in this Paper

Malignant Neoplasms
Clinical Trials
Double-Blind Method
Heparin
Neutropenia
Randomization
Catheter Device
Taurolidine
Prophylactic Treatment
Health Center
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Taurolidine-citrate lock solution for prevention of endoluminal central venous catheter infection in neutropenic hematological patients: a randomized, double-blind, placebo-controlled trial (TAURCAT)

Antimicrobial Agents and Chemotherapy

Nov 11, 2019

Carlota GudiolJordi Carratalà

PMID: 31712211

DOI: 10.1128/aac.01521-19

Abstract

Background: Infection of long-term central venous catheters (CVCs) remains a challenge in the clinical management of cancer patients. We aimed to determine whether a lock solution with taurolidine-citrate-heparin would be more effective than placebo for preventing non-tunnelled CVC infe...read more

Mentioned in this Paper

Malignant Neoplasms
Clinical Trials
Double-Blind Method
Heparin
Neutropenia

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