TB or not TB? Fishing for Molecules Making Permissive granulomas

Cell Host & Microbe
Stefan Ehlers

Abstract

Focal accumulations of mononuclear cells, called granulomas, are a hallmark of mycobacterial infections. A common misconception is that granulomas are uniformly protective. In transparent zebrafish larvae infected with Mycobacterium marinum, Volkman et al. demonstrate an interaction of mycobacteria with epithelial cells that helps recruit macrophages to the granuloma as "feeder cells."

References

Jun 25, 2009·Protein Science : a Publication of the Protein Society·Christopher T VeldkampBrian F Volkman

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Citations

Oct 23, 2013·PloS One·Parul Shrivastava, Tamishraha Bagchi
Jun 29, 2010·Immunobiology·Kerstin WalterStefan Ehlers

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