Tbx3-Mediated Regulation of Cardiac Conduction System Development and Function: Potential Contributions of Alternative RNA Processing

Pediatric Cardiology
Brian P DelisleAnne M Moon

Abstract

In this article, we provide a brief summary of work by us and others to discover the molecular underpinnings of early conduction system development and function. We focus on how the multifunctional protein Tbx3 contributes to acquisition and homeostasis of the tissue-specific properties of the sinoatrial and atrioventricular nodes. We also provide unpublished, preliminary findings supporting the role of Tbx3-regulated alternative RNA processing in the developing conduction system.

References

Mar 3, 1995·The Journal of Biological Chemistry·T Tomonaga, D Levens
Dec 10, 1999·The Journal of Clinical Investigation·D W BensonJ D Kugler
Oct 5, 2002·Nucleic Acids Research·Laura A Cassiday, L James Maher
Dec 28, 2002·Proceedings of the National Academy of Sciences of the United States of America·Benjamin P LewisSteven E Brenner
Feb 21, 2003·Gene·Laurent DupaysMagali Théveniau-Ruissy
Jul 30, 2003·Circulation·Arie O VerkerkE Etienne Verheijck
Oct 3, 2003·Trends in Cardiovascular Medicine·Dina C Myers, Glenn I Fishman
Nov 11, 2003·Journal of the American College of Cardiology·Doff B McElhinneyElizabeth Goldmuntz
Apr 20, 2004·Cardiovascular Research·Ben N G Giepmans
Jun 15, 2004·Current Opinion in Structural Biology·Liana F LareauSteven E Brenner
Aug 18, 2004·Circulation·Donald M Lloyd-JonesEmelia J Benjamin
Oct 23, 2004·The Journal of Physiology·Céline MarionneauSophie Demolombe
Jan 29, 2005·Genomics·Curtis L AndersonRudolf Werner
Feb 9, 2005·Journal of Molecular and Cellular Cardiology·Andrew L LundquistAlfred L George
Jul 5, 2005·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Bi-Hua TanJonathan C Makielski
Aug 11, 2005·Nucleic Acids Research·Esther A SuswamPeter H King
Apr 25, 2006·American Journal of Physiology. Heart and Circulatory Physiology·Bi-Hua TanJonathan C Makielski
May 2, 2006·Advances in Cardiology·M R BoyettH Dobrzynski
Jun 20, 2006·Biochemical and Biophysical Research Communications·Alicia Lundby, Søren-Peter Olesen
Oct 24, 2006·Trends in Cardiovascular Medicine·Maria M KreuzbergFeliksas F Bukauskas
Jan 11, 2007·Circulation·Dao W WangAlfred L George
May 3, 2007·Genes & Development·Willem M H HoogaarsVincent M Christoffels
Aug 30, 2007·Nature Reviews. Genetics·Guey-Shin Wang, Thomas A Cooper
May 10, 2008·Circulation Research·Martijn L BakkerVincent M Christoffels
Jul 16, 2008·Physiological Reviews·Matteo E Mangoni, Joël Nargeot
Jan 6, 2009·Circulation. Arrhythmia and Electrophysiology·Eva DelpónCharles Antzelevitch
Mar 17, 2009·Cell Communication and Signaling : CCS·Hashem A DboukRabih S Talhouk
Oct 24, 2009·FEBS Letters·Tobias MaierLuis Serrano
Nov 26, 2009·American Journal of Medical Genetics. Part a·Helen LindenUsha Kini
Jan 12, 2010·Nature Genetics·Arne PfeuferSusan R Heckbert

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Conduction System

The cardiac conduction system is a specialized tract of myocardial cells responsible for maintaining normal cardiac rhythm. Discover the latest research on the cardiac conduction system here.

© 2021 Meta ULC. All rights reserved