Tc-99m MIBI scintigraphy in tall cell variant of papillary thyroid carcinoma with negative radioiodine scan

Clinical Nuclear Medicine
Meryem Kaya, Tevfik Fikret Cermik

Abstract

We report on a 45-year-old man who had a mass on the wall of the anterior right hemithorax. An excisional biopsy indicated carcinoma metastasis from thyroid malignancy. Tc-99m methoxyisobutyl isonitrile (MIBI) scintigraphy revealed markedly increased activity on the left side of the thyroid and the thoracic wall mass. Postoperative histology revealed a tall cell variant of papillary thyroid carcinoma. Whole body scintigraphy after radioiodine treatment was negative twice. However, Tc-99m MIBI and bone scintigraphy showed multiple soft tissue and bone metastases in the follow-up period. He died 3 years later because of complications of distant lung metastases.

References

Dec 1, 1992·Aging : Clinical and Experimental Research·D CasaraB Busnardo
Jul 1, 1991·Seminars in Nuclear Medicine·G A Beller, D D Watson
Oct 1, 1986·The Journal of Clinical Endocrinology and Metabolism·M SchlumbergerC Parmentier
Jan 29, 1998·The New England Journal of Medicine·M J Schlumberger
Dec 11, 2003·European Journal of Nuclear Medicine and Molecular Imaging·Masahiro IwataJunji Konishi
Mar 30, 2004·Journal of Surgical Oncology·Mark SywakTravis Ogilvie
Nov 14, 2006·Human Pathology·Jean Jacques MichelsStephane Bardet
Nov 25, 2006·Thyroid : Official Journal of the American Thyroid Association·Domenico RubelloMilton Gross

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Citations

Apr 13, 2018·Journal of the Endocrine Society·Georgios E PapadakisGerasimos P Sykiotis

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