Tc-99m red blood cell imaging in a patient with blue rubber bleb nevus syndrome

Clinical Nuclear Medicine
Rajkumar YarlagaddaMichael M Graham

Abstract

Blue rubber bleb nevus syndrome, first discovered in 1860 by Gascoyen, is a rare syndrome characterized by multiple venous malformations (hemangiomas) of the skin and in the gastrointestinal tract. These hemangiomas may be found in the skin, GI tract, central nervous system, thyroid, parotid, eyes, oral cavity, musculoskeletal system, lungs, kidneys, liver, spleen, and bladder, and carry a significant potential for serious bleeding. We report a case of a 9-year-old patient who presented with bloody stools and was referred for localization of the bleeding site. A Tc-99m labeled red blood cell (RBC) scan showed no evidence of active lower GI bleeding but demonstrated multiple venous malformations throughout the body. Tc-99m labeled red blood cell imaging may be helpful to delineate the extent of involvement in patients with blue rubber bleb nevus syndrome.

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Citations

Jan 25, 2013·AJR. American Journal of Roentgenology·Gerald G Behr, Craig M Johnson
Sep 11, 2013·Indian Journal of Nuclear Medicine : IJNM : the Official Journal of the Society of Nuclear Medicine, India·Sampath SanthoshBhagwant Rai Mittal
Mar 23, 2020·The Journal of Dermatology·Hidefumi MimuraSatoru Sasaki
Mar 25, 2020·Japanese Journal of Radiology·Hidefumi MimuraSatoru Sasaki
Mar 24, 2020·Pediatrics International : Official Journal of the Japan Pediatric Society·Hidefumi MimuraSatoru Sasaki

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