Get paper from

journal cover

TCF7L2 is a master regulator of insulin production and processing

Human Molecular Genetics

Dec 15, 2014

Yuedan ZhouOla Hansson

Get paper from

Abstract

Genome-wide association studies have revealed >60 loci associated with type 2 diabetes (T2D), but the underlying causal variants and functional mechanisms remain largely elusive. Although variants in TCF7L2 confer the strongest risk of T2D among common variants by presumed effects on is...read more

Mentioned in this Paper

NKX6-2 gene
Cell Secretion
Gene Expression
NEUROD1 protein, human
Transcription Factor 7-Like 2
PCSK2 gene
MAFA protein, human
SLC30A8 gene
Basic Helix-Loop-Helix Transcription Factors
Single Nucleotide Polymorphism
2
114
Paper Details
References
    • References76
    • Citations36
    • References76
    • Citations36
  • TCF7L2 is a master regulator of insulin production and processing

    Human Molecular Genetics

    Dec 15, 2014

    Yuedan ZhouOla Hansson

    PMID: 25015099

    DOI: 10.1093/hmg/ddu359

    Abstract

    Genome-wide association studies have revealed >60 loci associated with type 2 diabetes (T2D), but the underlying causal variants and functional mechanisms remain largely elusive. Although variants in TCF7L2 confer the strongest risk of T2D among common variants by presumed effects on is...read more

    Mentioned in this Paper

    NKX6-2 gene
    Cell Secretion
    Gene Expression
    NEUROD1 protein, human
    Transcription Factor 7-Like 2
    2
    114

    Related Papers

    Paper Details
    References
    • References76
    • Citations36
    • References76
    • Citations36
  • Get paper from

    © 2019 Meta ULC. All rights reserved.

    Hi! We use cookies on this site for analytics purposes. Visit our cookie policy to learn more. By continuing to use our services or closing this banner, you consent to our use of cookies.

    /papers/tcf7l2-is-a-master-regulator-of-insulin/25015099