PMID: 9655361Jul 9, 1998Paper

Technetium-99m-dimercaptosuccinic acid renal scintigraphy in children over 5 years

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
A VanderfaeillieAmy Piepsz

Abstract

We retrospectively evaluated the frequency of renal scintigraphic abnormalities in children over 5 years admitted with a first symptomatic urinary tract infection (UTI). Among 261 children investigated, we found only 23 over 5 years having had technetium-99m-dimercaptosuccinic acid scintigraphy during the acute phase of a first UTI. Obvious scintigraphic abnormalities were detected in 14 children (15 kidneys): 12 kidneys showed focal cortical defects and 3 were small and deformed. Ultrasound was normal in 7 of the 15 kidneys with abnormal scintigraphy and in all the kidneys with normal scintigraphy. Among the 12 kidneys with focal cortical lesions, 8 kidneys returned to normal or improved considerably 2-12 months after initial work-up. In conclusion, in children over 5 years admitted with a first symptomatic UTI, the frequency of scintigraphic abnormalities is high and a strategy based only on ultrasound data would miss about 50% of the abnormal kidneys.

Citations

Aug 6, 2005·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Neamatollah AtaeiMosa Khorasani
Nov 17, 2001·Nuclear Medicine Communications·A Piepsz
Apr 14, 2000·Current Opinion in Pediatrics·S Hellerstein
Dec 17, 2005·Seminars in Nuclear Medicine·Amy Piepsz, Hamphrey R Ham

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