Technetium-99m tetrofosmin myocardial perfusion scan: comparison of 1-day and 2-day protocols

European Journal of Nuclear Medicine
T K YongS E Clarke

Abstract

Nineteen patients with angina were recruited in this study for comparison of two 1-day protocols (stress-4h rest and rest-4-h stress) and a 2-day protocol of technetium-99m tetrofosmin single-photon emission tomography (SPET). All of them underwent coronary angiography before or after the study. Exercise stress-rest study and rest-stress study were performed on two consecutive days. Delayed imaging was performed before the rest injection on the 2nd day. The stress study on the 1st day and rest study on the 2nd day were considered as a 2-day protocol. The 1-day stress-rest protocol had a sensitivity of 100% (18/18) and an accuracy of 100% (19/19) in diagnosing ischaemic heart disease. The 1-day rest-stress protocol had a sensitivity of 94.4% (17/18) and an accuracy of 94.7% (18/19). These differences were not statistically significant (P=0.5 for sensitivity and accuracy). There was also no statistically significant difference between the two protocols in the diagnosis of ischaemic heart disease in individual artery territories. For the left descending artery, sensitivity was 88.2% (15/17) vs 76.5% (13/17) (P=0.48) for the stress-rest and rest-stress studies respectively. For the left circumflex artery, sensitivity was 90% (9/10)...Continue Reading

Citations

Feb 13, 1999·Clinical Nuclear Medicine·N HattoriJ Konishi
Jun 1, 2007·European Journal of Clinical Investigation·T ToriyamaY Dohi
Oct 22, 2020·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Ian S Armstrong

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