Technical assessment of whole body angiography and cardiac function within a single MRI examination

Clinical Radiology
Stephen J GandyJ Graeme Houston

Abstract

To evaluate a combined protocol for simultaneous cardiac MRI (CMR) and contrast-enhanced (CE) whole-body MR angiography (WB-MRA) techniques within a single examination. Asymptomatic volunteers (n = 48) with low-moderate risk of cardiovascular disease (CVD) were recruited. The protocol was divided into four sections: (1) CMR of left ventricle (LV) structure and function; (2) CE-MRA of the head, neck, and thorax followed by the distal lower limbs; (3) CMR LV "late gadolinium enhancement" assessment; and (4) CE-MRA of the abdomen and pelvis followed by the proximal lower limbs. Multiple observers undertook the image analysis. For CMR, the mean ejection fraction (EF) was 67.3 ± 4.8% and mean left ventricular mass (LVM) was 100.3 ± 22.8 g. The intra-observer repeatability for EF ranged from 2.1-4.7% and from 9-12 g for LVM. Interobserver repeatability was 8.1% for EF and 19.1 g for LVM. No LV delayed myocardial enhancement was observed. For WB-MRA, some degree of luminal narrowing or stenosis was seen at 3.6% of the vessel segments (involving n = 29 of 48 volunteers) and interobserver radiological opinion was consistent in 96.7% of 1488 vessel segments assessed. Combined assessment of WB-MRA and CMR can be undertaken within a single...Continue Reading

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Citations

Jan 27, 2016·The International Journal of Cardiovascular Imaging·Jonathan R Weir-McCallJ Graeme Houston
Aug 24, 2016·European Heart Journal Cardiovascular Imaging·Jonathan R Weir-McCallJ Graeme Houston
Feb 1, 2018·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Jonathan R Weir-McCallJ Graeme Houston
Jul 23, 2018·Clinical Radiology·J R Weir-McCallJ G Houston

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Software Mentioned

SPSS
Argus
Siemens Multi - modality Work Platform
Carestream PACS Client Suite

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