Technical Note: Deep learning based MRAC using rapid ultrashort echo time imaging

Medical Physics
Hyungseok JangAlan B McMillan

Abstract

In this study, we explore the feasibility of a novel framework for MR-based attenuation correction for PET/MR imaging based on deep learning via convolutional neural networks, which enables fully automated and robust estimation of a pseudo CT image based on ultrashort echo time (UTE), fat, and water images obtained by a rapid MR acquisition. MR images for MRAC are acquired using dual echo ramped hybrid encoding (dRHE), where both UTE and out-of-phase echo images are obtained within a short single acquisition (35 s). Tissue labeling of air, soft tissue, and bone in the UTE image is accomplished via a deep learning network that was pre-trained with T1-weighted MR images. UTE images are used as input to the network, which was trained using labels derived from co-registered CT images. The tissue labels estimated by deep learning are refined by a conditional random field based correction. The soft tissue labels are further separated into fat and water components using the two-point Dixon method. The estimated bone, air, fat, and water images are then assigned appropriate Hounsfield units, resulting in a pseudo CT image for PET attenuation correction. To evaluate the proposed MRAC method, PET/MR imaging of the head was performed on e...Continue Reading

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Citations

Mar 13, 2019·Journal of Applied Clinical Medical Physics·Fang LiuAlan B McMillan
Mar 13, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Fang LiuRichard Kijowski
May 22, 2019·The British Journal of Radiology·Daniel JarrettMark J Gooding
Sep 19, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Hyungseok JangJiang Du
Dec 12, 2018·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Fang Liu
May 18, 2020·European Journal of Nuclear Medicine and Molecular Imaging·Isaac ShiriHabib Zaidi
Dec 3, 2020·Physics in Medicine and Biology·Ciprian Catana
Dec 12, 2020·Journal of Applied Clinical Medical Physics·Tonghe WangXiaofeng Yang
Feb 10, 2021·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Yasheng ChenHongyu An
Nov 13, 2020·BJR Open·Georg Schramm, Claes Nøhr Ladefoged
Mar 26, 2021·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Hossein ArabiHabib Zaidi
Aug 19, 2021·Medical Physics·Maria Francesca SpadeaJoao Seco
Jan 15, 2022·Annals of Nuclear Medicine·Satoshi Minoshima, Donna Cross

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