Technical Note: Experimental verification of magnetic field-induced beam deflection and Bragg peak displacement for MR-integrated proton therapy

Medical Physics
Sonja M SchellhammerAswin L Hoffmann

Abstract

Given its sensitivity to anatomical variations, proton therapy is expected to benefit greatly from integration with magnetic resonance imaging for online anatomy monitoring during irradiation. Such an integration raises several challenges, as both systems mutually interact. The proton beam will experience quasi-continuous energy loss and energy-dependent electromagnetic deflection at the same time, giving rise to a deflected beam trajectory and an altered dose distribution with a displaced Bragg peak. So far, these effects have only been predicted using Monte Carlo and analytical models, but no clear consensus has been reached and experimental benchmark data are lacking. We measured proton beam trajectories and Bragg peak displacement in a homogeneous phantom placed inside a magnetic field and compared them to simulations. Planar dose distributions of proton pencil beams (80-180 MeV) traversing the field of a 0.95 T NdFeB permanent magnet while depositing energy in a PMMA slab phantom were measured using EBT3 radiochromic films and simulated using the Geant4 toolkit. Deflected beam trajectories and the Bragg peak displacement were extracted from the measured planar dose distributions and compared against the simulations. The la...Continue Reading

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Citations

Nov 23, 2018·Physics in Medicine and Biology·Sonja M SchellhammerJörg Pawelke
Dec 24, 2018·Physics in Medicine and Biology·A LührA L Hoffmann
Oct 30, 2019·Medical Physics·Fatima Padilla-CabalHermann Fuchs
May 31, 2020·Radiation Oncology·Aswin HoffmannKatia Parodi
Dec 17, 2020·Medical Physics·Hermann FuchsDietmar Georg
Aug 19, 2021·Physics in Medicine and Biology·Maryam MoteabbedThomas R Bortfeld
Oct 29, 2021·Physics in Medicine and Biology·Harald PaganettiBrian Winey

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