Technique and results of interstitial laser coagulation

World Journal of Urology
R Muschter, A Hofstetter

Abstract

By use of thermal "ablation" techniques to apply heat to the prostate from the urethra, the coagulation volume is limited by the limited penetration depth of suitable radiation sources, e.g., lasers, and by heat conduction. Secondarily, the coagulated tissue is removed by sloughing. Interstitial heat application was expected to overcome these problems. Our initial in vitro and animal studies using different light guides for interstitial Nd:YAG laser radiation showed that small, carbonized lesions were created by bare fibers, whereas large, homogeneous coagulation zones measuring up to 2 cm in diameter were produced by specially designed ITT (interstitial thermotherapy) fibers, which secondarily resulted in marked volume reduction by atrophy. Further experiments using such applicators resulted in an operation technique suitable for clinical routine in the treatment of symptomatic benign prostatic hyperplasia (BPH). These laser applicators are inserted into the prostate either transurethrally through a cystoscope under direct vision or percutaneously from the perineum under transrectal ultrasound guidance. The number of placements depends on the size and configuration of the gland. Radiation parameters were optimized for each sys...Continue Reading

Citations

Jun 22, 2006·Der Urologe. Ausg. A·O ReichC Stief
Jun 28, 2005·Current Urology Reports·Werner W Hochreiter, Roger M Müller
Dec 20, 1999·Seminars in Roentgenology·S R Potter, A W Partin
Dec 26, 2001·Urology·M L Blute, T Larson
Nov 19, 2003·Journal of Endourology·Raymond J Leveillee, Michael F Hoey
Nov 19, 2003·Journal of Endourology·M Pilar LagunaJean J M C H De La Rosette
Jun 26, 2009·Der Urologe. Ausg. A·R Muschter
Sep 16, 1998·Mayo Clinic Proceedings·A P Perlmutter, R Muschter
Oct 29, 2004·International Journal of Urology : Official Journal of the Japanese Urological Association·Naoki TeradaAkito Terai
May 16, 2006·The Journal of Urology·Hooman DjaladatGholamreza Pourmand
Jan 29, 2005·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·K Shinohara
Oct 13, 2006·Current Opinion in Urology·P J Gilling, M R Fraundorfer
Dec 1, 1996·Journal of Clinical Laser Medicine & Surgery·J FeyhE Kastenbauer
Jul 8, 2021·Current Opinion in Urology·Mark TaratkinDmitry Enikeev

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Cardiac Conduction System

The cardiac conduction system is a specialized tract of myocardial cells responsible for maintaining normal cardiac rhythm. Discover the latest research on the cardiac conduction system here.