Technique for the administration of high-dose-rate brachytherapy to the bile duct using a nasobiliary catheter

Brachytherapy
Christopher L DeufelMichael G Haddock

Abstract

Cholangiocarcinoma patients who are potential candidates for liver transplantation may be treated with high-dose-rate (HDR) brachytherapy using a minimally invasive nasobiliary catheter in an effort to escalate the radiotherapy dose to the tumor and maximize local control rates. This work describes the equipment, procedures, and quality assurance (QA) that enables successful administration. This work describes the nasobiliary catheter placement, simulation, treatment planning, treatment delivery, and QA. In addition, a chart review was performed of all patients who received endoscopic retrograde cholangiopancreatography for HDR bile duct brachytherapy at our institution from 2007 to 2017. The review evaluated how many patients were treated and the number of patients who could not be treated because of anatomic and/or equipment limitations. From 2007 to 2017, 122 cholangiocarcinoma patients have been treated with HDR brachytherapy using a nasobiliary catheter. Three patients underwent catheter placement but did not receive brachytherapy treatment due to catheter migration between placement and treatment or because the HDR afterloader was unable to extend the source wire into the treatment site. Periodic QA is recommended for ens...Continue Reading

Citations

Feb 13, 2021·Journal of Personalized Medicine·Ivo BoškoskiGuido Costamagna
Mar 13, 2021·World Journal of Hepatology·Alina Ioana TantauVoicu Mercea
Apr 23, 2021·VideoGIE : an Official Video Journal of the American Society for Gastrointestinal Endoscopy·Jerry Yung-Lun ChinVinay Chandrasekhara

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