Technique for the computation of lower leg muscle bulk from magnetic resonance images

Medical Engineering & Physics
Barry J BroderickGearóid Olaighin

Abstract

An unsupervised technique to estimate the relative size of a patient's lower leg musculature in vivo using magnetic resonance imaging (MRI) in the context of venous insufficiency is presented. This post-acquisition technique was designed to segment calf muscle bulk, which could be used to make inter- or intra-patient comparisons of calf muscle size in the context of unilateral leg ulcers and venous return. Pre-processing stages included partial volume reduction, intensity inhomogeneity correction and contrast equalization. The algorithm created a binary mask of voxels that fell within a computed threshold designated as representing muscle based on a 3-class fuzzy clustering approach. The segmentation was improved using a set of morphological operations to remove adipose tissue, spongy bone and cortical bone. The technique was evaluated for accuracy against a manual segmented ground truth. Results showed that the automatic technique performed sufficiently well in terms of accuracy and efficacy. The automatic method did not suffer from intra-observer variability.

References

Nov 1, 1996·Physics in Medicine and Biology·P GibbsA Horsman
Jan 14, 1998·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·J M ElbersL J Gooren
Jun 9, 1998·IEEE Transactions on Medical Imaging·M S Atkins, B T Mackiewich
Jun 22, 1999·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·S RajuE F Meydrech
Sep 14, 2000·European Journal of Applied Physiology·M C van BeekveltM T Hopman
Feb 13, 2001·Radiology·M R KausR Kikinis
Jul 3, 2002·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·G M LyonsP A Grace
Sep 25, 2004·Journal of Magnetic Resonance Imaging : JMRI·Vincenzo PositanoLuigi Landini
Sep 17, 2005·American Journal of Surgery·Heather WrightJoseph Crowe
Oct 26, 2005·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·M Clarke MoloneyP A Grace
Apr 6, 2006·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Jayaram K UdupaJames Woodburn
May 10, 2006·British Journal of Hospital Medicine·Ian YoungAndrew Taylor
May 13, 2006·IEEE Transactions on Medical Imaging·Olivier SalvadoDavid L Wilson
Oct 19, 2006·Journal of Wound Care·M Clarke-MoloneyE Kavanagh
Aug 8, 2007·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·S J LordN Houssami
Jan 1, 1994·IEEE Transactions on Medical Imaging·A P ZijdenbosA C Palmer
Jan 1, 1989·IEEE Transactions on Medical Imaging·D N KennedyV R Caviness
Nov 28, 2008·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Manuela UndurragaPierre Loubeyre
Jan 1, 2006·International Journal of Biomedical Imaging·Zujun Hou
Jan 1, 2006·International Journal of Biomedical Imaging·Olivier SalvadoDavid L Wilson

❮ Previous
Next ❯

Citations

Mar 2, 2013·Journal of Magnetic Resonance Imaging : JMRI·Victor A CheuyMichael J Mueller
Oct 4, 2011·Journal of Magnetic Resonance Imaging : JMRI·Paul K CommeanMichael J Mueller
Aug 14, 2015·Journal of Magnetic Resonance Imaging : JMRI·Sara OrgiuGiovanna Rizzo
Aug 12, 2014·Journal of Magnetic Resonance Imaging : JMRI·Anette KarlssonOlof Dahlqvist Leinhard
Oct 12, 2011·Current Opinion in Supportive and Palliative Care·Alisdair J MacDonaldVickie Baracos
Feb 8, 2018·PloS One·Janne WestOlof Dahlqvist Leinhard

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cajal Bodies & Gems

Cajal bodies or coiled bodies are dense foci of coilin protein. Gemini of Cajal bodies, or gems, are microscopically similar to Cajal bodies. It is believed that Cajal bodies play important roles in RNA processing while gems assist the Cajal bodies. Find the latest research on Cajal bodies and gems here.