PMID: 16533471Mar 15, 2006Paper

Techniques and results of neurolysis for chronic pancreatitis and pancreatic cancer pain

Current Gastroenterology Reports
Marc Noble, Frank Gress

Abstract

Chronic abdominal pain can be associated with benign and malignant disease. Pain associated with pancreatic cancer and chronic pancreatitis can be severely debilitating, with significant impairment in quality of life. Frequently, chronic abdominal pain is not adequately responsive to conventional medical therapies, including nonsteroidal anti-inflammatory drugs and opioids. For this reason, alternative methods to alleviate pain have been developed. Celiac plexus neurolysis and celiac block involve injecting an agent at the celiac axis, with the goal of either selectively destroying the celiac plexus or temporarily blocking visceral afferent nociceptors to alleviate chronic abdominal pain. Agents most commonly used for this purpose include alcohol or phenol for neurolysis and bupivacaine and triamcinolone for temporary block. Methods to administer such agents to the celiac ganglion include CT imaging, percutaneous ultrasound, fluoroscopy, endoscopic ultrasound, or surgery (ganglionectomy). Response rates and complications vary depending on technique but are relatively low. This review highlights the techniques of celiac plexus neurolysis and celiac block and their status in the treatment of chronic pancreatitis and pancreatic ca...Continue Reading

References

Dec 1, 1979·AJR. American Journal of Roentgenology·V Hegedüs
Nov 1, 1979·Anesthesia and Analgesia·E M WardR C Bahn
Feb 1, 1992·Journal of Pain and Symptom Management·M ZenzM Tryba
Apr 1, 1990·Radiology·R P Lieberman, S D Waldman
Jan 1, 1989·Pain·A H Lebovits, M Lefkowitz
Mar 1, 1989·Pain·David E Weissman, David J Haddox
Sep 1, 1987·Anesthesia and Analgesia·D L BrownE L Quiel
Feb 1, 1995·Anesthesia and Analgesia·E EisenbergT C Chalmers
Apr 1, 1994·Clinical Pharmacology and Therapeutics·M M Reidenberg, R K Portenoy
May 1, 1993·Journal of the Royal Society of Medicine·D D Davies
May 1, 1993·The British Journal of Surgery·T NagakawaY Higashino
Dec 1, 1996·Gastrointestinal Endoscopy·M J Wiersema, L M Wiersema
Mar 1, 1997·Surgical Endoscopy·M CaratozzoloL Angelini
Apr 1, 1997·Gastrointestinal Endoscopy Clinics of North America·N HaradaL M Wiersema
Apr 29, 1998·Regional Anesthesia and Pain Medicine·S Mercadante, F Nicosia
Dec 20, 1999·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·E K Abdalla, S R Schell
Aug 23, 2001·Journal of Pain and Symptom Management·S KrishnaJ Donahoo
Aug 28, 2001·Gastrointestinal Endoscopy·N T GunaratnamM J Wiersema
Dec 1, 2001·Journal of Pain and Symptom Management·J H VrankenJ J de Lange
Dec 12, 2001·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·P Y MarcyB Descamps
May 9, 2002·Journal of Pain and Symptom Management·Sebastiano MercadantePatrizia Villari
Dec 23, 2003·The American Journal of Gastroenterology·Markus WehlerThomas Schneider
Apr 26, 2005·Current Oncology Reports·Gregory Friberg, Hedy Lee Kindler
Aug 27, 2005·World Journal of Gastroenterology : WJG·Andrzej BasinskiZbigniew Sledzinski

❮ Previous
Next ❯

Citations

Oct 15, 2011·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Avinash KambadakoneRonald S Arellano
Dec 5, 2015·Cardiovascular and Interventional Radiology·J RickeP R Mertens
May 18, 2011·Clinical Oncology : a Journal of the Royal College of Radiologists·J G de Courcy
Jun 1, 2010·Best Practice & Research. Clinical Gastroenterology·Güralp O CeyhanHelmut Friess
Aug 30, 2007·Gastrointestinal Endoscopy·John R Saltzman
May 30, 2007·Gastroenterology Clinics of North America·Kenneth E FasanellaDavid C Whitcomb
Jan 1, 2010·Cancers·Mariam HameedMichael Erdek
Sep 9, 2015·The American Journal of Hospice & Palliative Care·Mark R EdelsteinMalcolm K Sydnor
Jan 11, 2011·The Korean Journal of Pain·Seo Kyung ShinKyung Bong Yoon
Nov 29, 2012·The Cancer Journal·Claudius Conrad, Keith D Lillemoe
Jun 13, 2020·Current Pain and Headache Reports·Ivan UritsOmar Viswanath
Jun 14, 2019·Visceral Medicine·Alexander WaldthalerJ-Matthias Löhr

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.