Techniques for measuring renal transit time

European Journal of Nuclear Medicine
C D RussellE V Dubovsky

Abstract

A variety of techniques have been used for quantitative estimation of renal transit time. We compared different indices of transit time in a group of 30 patients having baseline and ACE inhibitor technetium-99m mercaptoacetyltriglycine (MAG3) renography prior to arteriography: peak time, mean transit time, and the ratio of background-subtracted counts at 20 min to those at 3 min. Each index was calculated from whole-kidney ROI, cortical ROI, and cortical factor (by factor analysis). The strongest correlations between angiographic percent of stenosis and transit time index were observed for the peak time (Spearman p=0.469, n=53, P <0.005) and for the R20/3 (again p=0.469, n=53, P <0.005) using the whole-kidney ROI and using only the baseline data without captopril. (Spearman's p is simply the correlation coefficient calculated from rank in list, which allows for nonlinear correlation.) Thus simple indices of transit time (whole-kidney peak time and R20/3) correlated as well with the observed pathology as did more complicated methods that required deconvolution, factor analysis, or selection of a cortical ROI.

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Citations

Nov 7, 2000·Nuclear Medicine Communications·H Rajabi, G S Pant
Oct 19, 2001·Nuclear Medicine Communications·J D KuyvenhovenA Piepsz
Apr 22, 2004·Nuclear Medicine Communications·Jacob D KuyvenhovenAmy Piepsz
Jan 11, 2005·Nuclear Medicine Communications·Jacob D KuyvenhovenAmy Piepsz
Feb 4, 2014·Seminars in Nuclear Medicine·Ayşe Aktaş
Dec 22, 2007·Seminars in Nuclear Medicine·Emmanuel DurandUNKNOWN International Scientific Committee of Radionuclides in Nephrourology (ISCORN)
Dec 23, 1999·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·P Y BarthezD J Chew
Sep 26, 2003·Nuclear Medicine Communications·J D KuyvenhovenA Piepsz
Jun 10, 2021·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Gyanendra Ravindra SharmaAnshu Gyanendra Sharma

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