PMID: 8939712Nov 1, 1996Paper

Telomerase: anti-cancer target or just a fascinating enzyme?

Chemistry & Biology
S E Hamilton, D R Corey

Abstract

Telomerase activity is upregulated in most types of malignant tumor. Highly selective small molecule inhibitors will be needed to understand the biological basis for this observation and to determine if telomerase is a viable target for chemotherapy.

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Citations

Mar 31, 2000·Pharmacology & Therapeutics·S NeidleM A Read
May 14, 1999·Drug Discovery Today·A E Pitts, D R Corey
Sep 30, 1998·Proceedings of the National Academy of Sciences of the United States of America·A E Pitts, D R Corey
Feb 7, 2001·Cancer Investigation·A J Davis, L L Siu
Jan 24, 2003·Expert Opinion on Therapeutic Targets·Terace M Fletcher
Jan 5, 2001·Expert Opinion on Investigational Drugs·P J Perry, T C Jenkins
Jun 22, 1999·Chemistry & Biology·S E HamiltonD R Corey
Oct 19, 2000·Anti-cancer Drugs·L R Kelland
Nov 21, 1998·Journal of Medicinal Chemistry·P J PerryS Neidle

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