Telomere capping in Drosophila: dealing with chromosome ends that most resemble DNA breaks

Chromosoma
Yikang S Rong

Abstract

Telomere caps prevent chromosome ends from being recognized as DNA double-strand breaks (DSBs). Unlike most organisms studied, the telomere-capping function of Drosophila does not require a specific sequence. Without this sequence component, Drosophila telomeres most resemble DNA breaks and, thus, represent a simpler system for the study of telomere capping. I review recent progress in Drosophila telomere studies, and challenge the notion that Drosophila may not be a relevant model for the study of telomere maintenance.

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Citations

Feb 3, 2009·Proceedings of the National Academy of Sciences of the United States of America·Grazia D RaffaMaurizio Gatti
Jun 13, 2009·Proceedings of the National Academy of Sciences of the United States of America·Guanjun GaoYikang S Rong
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Jul 31, 2013·Genetics·Natalia WesolowskaYikang S Rong
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Feb 9, 2021·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·Kinyo OnYasuko Kato
Apr 25, 2015·Journal of Cell Science·Raphaëlle Dubruille, Benjamin Loppin

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