Telomere length and fetal programming: A review of recent scientific advances

American Journal of Reproductive Immunology : AJRI
Valerie WhitemanHamisu M Salihu

Abstract

We sought to synthesize a comprehensive literature review comprising recent research linking fetal programming to fetal telomere length. We also explored the potential effects fetal telomere length shortening has on fetal phenotypes. Utilizing the PubMed database as our primary search engine, we retrieved and reviewed 165 articles of published research. The inclusion criteria limited the articles to those that appeared within the last ten years, were pertinent to humans, and without restriction to language of publication. Our results showed that socio-demographic factors like age, sex, genetic inheritance, and acquired disease impact telomere length. Further, we found several maternal characteristics to be associated with fetal telomere length shortening, and these include maternal chemical exposure (eg, tobacco smoke), maternal stress during pregnancy, maternal nutritional and sleeping disorders during pregnancy as well as maternal disease status. Due to paucity of data, our review could not synthesize evidence directly linking fetal phenotypes to telomere length shortening. Although the research summarized in this review shows some association between determinants of intrauterine programming and fetal telomere length, there i...Continue Reading

References

Sep 14, 2006·Development·Hanna K A Mikkola, Stuart H Orkin
Sep 22, 2007·Early Human Development·Hamisu M Salihu, Roneé E Wilson
Jul 23, 2009·Obstetrics and Gynecology·Hamisu M SalihuVictoria Belogolovkin
Dec 17, 2010·Gynecologic and Obstetric Investigation·Isil CokerOya Halicioglu
Nov 1, 2012·Science Signaling·Sonja EntringerPathik D Wadhwa
Oct 16, 2013·Human Pathology·Tania L SlatterNoelyn A Hung
Jun 14, 2014·Journal of Developmental Origins of Health and Disease·H M SalihuA P Alio
Sep 1, 2014·American Journal of Obstetrics and Gynecology·Hamisu M SalihuValerie Whiteman
May 14, 2016·World Journal of Clinical Pediatrics·Serafina PerroneGiuseppe Buonocore
May 20, 2016·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Patrick IpYu Lung Lau
Jun 15, 2016·Annual Review of Biochemistry·Celine E RieraAndrew Dillin
Jun 28, 2016·Progress in Neuro-psychopharmacology & Biological Psychiatry·Mateus Luz LevandowskiRodrigo Grassi-Oliveira
Jul 1, 2016·Current Environmental Health Reports·Dries S Martens, Tim S Nawrot
Jul 5, 2016·World Journal of Methodology·Swetasmita MishraRima Dada
Jul 9, 2016·PLoS Genetics·Rivka C StoneAbraham Aviv
Jul 9, 2016·The European Respiratory Journal·Amparo EscribanoFrancisco Dasí
Jul 10, 2016·Molecular and Cellular Endocrinology·Summer Elshenawy, Rebecca Simmons
Jul 12, 2016·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·Yugo HiraiFuyuki Ishikawa
Jul 16, 2016·Journal of Exercise Rehabilitation·Yun-A Shin, Kyoung-Young Lee
Jul 22, 2016·The American Journal of Clinical Nutrition·Janet M WojcickiElissa Epel
Jul 28, 2016·Placenta·Tal Biron-ShentalAliza Amiel
Oct 25, 2016·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·C BickelC Sinning

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Citations

Mar 2, 2018·Annual Review of Clinical Psychology·Elissa S Epel, Aric A Prather
Jul 18, 2020·The Journal of Nutrition·Marie VahterFlorencia Harari
Mar 27, 2018·American Journal of Reproductive Immunology : AJRI·Shi-Bin ChengSurendra Sharma
Feb 1, 2020·The Science of the Total Environment·Citlalli Osorio-YáñezMartine Vrijheid
Oct 31, 2020·Frontiers in Physiology·Jossimara Polettini, Marcia Guimarães da Silva
Dec 24, 2020·International Journal of Molecular Sciences·Toshiko MinamotoSatoru Kyo
Mar 13, 2021·Clinical Chemistry and Laboratory Medicine : CCLM·Analia LesmanaUNKNOWN Harmonising Age Pathology Parameters in Kids Study Team
May 1, 2021·International Journal of Molecular Sciences·Eva PericuestaAlfonso Gutiérrez-Adán
Jul 25, 2021·International Journal of Molecular Sciences·Isabel Garcia-MartinRosalind M John

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