PMID: 6411353Aug 1, 1983Paper

Telomere regions in Drosophila share complex DNA sequences with pericentric heterochromatin

Cell
B S YoungM L Pardue

Abstract

A 12 kb fragment of Drosophila melanogaster DNA cloned in a lambda phage, lambda T-A, is shown by in situ hybridization to contain sequences homologous to DNA at the extreme ends of each of the polytene chromosomes and to the pericentric sequences present in the beta heterochromatin. This pattern of hybridization is seen for each of the four D. melanogaster stocks that have been studied. Most of the sequence in lambda T-A shows no detectable homology to DNA within the banded chromosome arms. (The only exception is what appears to be a short mobile element inserted in lambda T-A. This portion of lambda T-A hybridizes with internal arm sites that vary from stock to stock). Analysis of restriction fragments of genomic DNA indicates that the sequences in lambda T-A are homologous to complex sets of repeated sequences that differ from stock to stock in D. melanogaster. Some, but not all, of the members of these sets are underreplicated during polytenization in D. melanogaster. The sequences in lambda T-A are also homologous to complex sets of repeated sequences in the genomes of other Drosophila species belonging to the melanogaster species group. Pericentric and telomeric localization is conserved in these related species, although...Continue Reading

References

May 18, 1976·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·F Lemeunier, M A Ashburner
Jan 1, 1978·Cold Spring Harbor Symposia on Quantitative Biology·G M Rubin
Jan 1, 1978·Cold Spring Harbor Symposia on Quantitative Biology·W J PeacockR Appels
Mar 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·T ManiatisD G Kleid
May 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·B B Spear, J G Gall
Jan 1, 1971·Chromosoma·J G GallM L Polan
May 1, 1982·Cell·J W Szostak, E H Blackburn
Aug 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·A P Dowsett, M W Young
Nov 1, 1942·Proceedings of the National Academy of Sciences of the United States of America·B McClintock
Jan 1, 1946·Hereditas·G OESTERGREN, R PRAKKEN

❮ Previous
Next ❯

Citations

Jan 1, 1984·Human Genetics·P H Fitzgerald, C M Morris
Jun 1, 1991·Journal of Molecular Evolution·M Cohn, J E Edström
Apr 1, 1996·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·U PichI Schubert
Jul 9, 2010·Chromosoma·Christiane Rodriguez Gutierrez MadalenaEduardo Gorab
Jun 26, 2012·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Thiago FernandesEduardo Gorab
Jun 1, 1987·Molecular and Biochemical Parasitology·T PaceC Frontali
Feb 1, 1995·Trends in Genetics : TIG·J M Mason, H Biessmann
Apr 1, 1997·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R J Wellinger, D Sen
Oct 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·J M MasonM M Green
Oct 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·R J Donnelly, B I Kiefer
Nov 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·K L Traverse, M L Pardue
Apr 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·G L MiklosV Pirrotta
Oct 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·K ValgeirsdóttirM L Pardue
Nov 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·M E PetracekJ Berman
Jul 22, 1997·Proceedings of the National Academy of Sciences of the United States of America·P DimitriE Mei
Feb 1, 1993·The Journal of Cell Biology·Y HiraokaJ W Sedat
Mar 11, 1986·Nucleic Acids Research·R Yokoyama, M C Yao
Aug 11, 1989·Nucleic Acids Research·J F ChengC R Cantor
Jan 1, 1991·The Plant Cell·M W GanalS D Tanksley
Dec 1, 1995·Genome Génome / Conseil National De Recherches Canada·A ZambetakiP Mavragani-Tsipidou
Jun 1, 1996·Genome Génome / Conseil National De Recherches Canada·E PardaliP Mavragani-Tsipidou
Aug 12, 2005·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Harald BiessmannJames M Mason
Aug 12, 2005·Cytogenetic and Genome Research·M BerlocoS Pimpinelli
Sep 7, 2005·Genetics·Harald BiessmannJames M Mason
Jan 19, 2008·Genetics·Jennifer A AndersonCharles H Langley
Apr 1, 1985·Cell·J E O'TousaM L Applebury

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell eTOC

Cell is a scientific journal publishing research across a broad range of disciplines within the life sciences field. Discover the latest research from Cell here.