Telomeric Chromatin and TERRA.

Journal of Molecular Biology
Amandine Barral, Jérome Déjardin

Abstract

Chromatin function in telomeres is poorly understood, but it is generally viewed as repressive. Yet, telomeric DNA sequences are transcribed into long non-coding RNAs named TElomere Repeat-containing RNA (TERRA). As TERRA molecules mostly localize at telomeres, major research efforts have been made to understand their functions, and how TERRA transcription is regulated and affects telomere structure. This review describes the current state of knowledge about the nature of chromatin at telomeres, its functions, and the relation between chromatin structure and TERRA.

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Citations

Aug 23, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Tracy M Bryan
Sep 12, 2020·Human Molecular Genetics·Shir ToubianaSara Selig
Jun 5, 2021·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Shinichi NakagawaTetsuro Hirose

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