Tembotrione detoxification in 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitor-resistant Palmer amaranth (Amaranthus palmeri S. Wats.)

Pest Management Science
Anita KüpperTodd A Gaines

Abstract

Resistance to the 4-hydroxyphenylpyruvate dioxygenase (HPPD)-inhibiting herbicide tembotrione in an Amaranthus palmeri population from Nebraska (NER) has previously been confirmed to be attributable to enhanced metabolism. The objective of this study was to identify and quantify the metabolites formed in Nebraska susceptible (NES) and resistant (NER) biotypes. NER and NES formed the same metabolites. Tembotrione metabolism in NER differed from that in NES in that resistant plants showed faster 4-hydroxylation followed by glycosylation. The T50 value (time for 50% production of the maximum 4-hydroxylation product) was 4.9 and 11.9 h for NER and NES, respectively. This process is typically catalyzed by cytochrome P450 enzymes. Metabolism differences between NER and NES were most prominent under 28 °C conditions and herbicide application at the four-leaf stage. Further research with the aim of identifying the gene or genes responsible for conferring metabolic resistance to HPPD inhibitors should focus on cytochrome P450s. Such research is important because non-target-site-based resistance (NTSR) poses the threat of cross resistance to other chemical classes of HPPD inhibitors, other herbicide modes of action, or even unknown herbi...Continue Reading

References

Jul 18, 2001·Pest Management Science·G MitchellR A Wichert
Jun 27, 2002·Journal of Agricultural and Food Chemistry·Philip Alferness, Lawrence Wiebe
Nov 13, 2002·Plant Physiology·Jan Bart RosselBarry J Pogson
Apr 15, 2003·Journal of Molecular Biology·Pedro M CoutinhoBernard Henrissat
Jan 6, 2005·Pest Management Science·Michel MatringeOlivier Zink
May 25, 2006·Environmental Science & Technology·Alexandra Ter HalleClaire Richard
Dec 13, 2006·Trends in Plant Science·Joshua S YuanC Neal Stewart
Oct 4, 2007·Pest Management Science·Hanène ChaabaneJean-François Cooper
Mar 3, 2010·Annual Review of Plant Biology·Stephen B Powles, Qin Yu
May 15, 2012·The Arabidopsis Book·M Águila Ruiz-Sola, Manuel Rodríguez-Concepción
Mar 23, 2013·The Science of the Total Environment·Christophe CalvayracJean-Francois Cooper
Mar 27, 2013·Proceedings of the National Academy of Sciences of the United States of America·Ian CumminsRobert Edwards
Mar 25, 2014·The Plant Journal : for Cell and Molecular Biology·Todd A GainesRoland Beffa
Sep 20, 2016·Pest Management Science·Roberto BusiStephen Powles
Feb 23, 2017·Plant Science : an International Journal of Experimental Plant Biology·Arnaud DuhouxChristophe Délye

❮ Previous
Next ❯

Citations

Sep 12, 2018·Pest Management Science·Todd A GainesFranck E Dayan
Sep 16, 2018·The Plant Journal : for Cell and Molecular Biology·Maxwel C OliveiraStevan Z Knezevic
Oct 18, 2019·Plants·Mithila Jugulam, Chandrima Shyam
May 21, 2020·The Journal of Biological Chemistry·Todd A GainesFranck E Dayan
Sep 6, 2020·Ecotoxicology and Environmental Safety·Naincy RaniDinesh Tomar
Jun 22, 2021·Journal of Agricultural and Food Chemistry·Hengzhi WangJinxin Wang
Aug 28, 2021·Genes·Fidel González-Torralva, Jason K Norsworthy

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.