Temperament and character dimensions in bipolar I disorder: a comparison to healthy controls

Journal of Psychiatric Research
Shay T LoftusAnil K Malhotra

Abstract

Research on phenotypic markers of vulnerability to bipolar disorder has focused on the identification of personality traits uniquely associated with the illness. To expand knowledge in this area, we compared Cloninger's seven temperament and character dimensions in 85 euthymic/subsyndromal bipolar I inpatients and outpatients and 85 age and sex matched community controls. We also examined associations between Cloninger's personality traits and mood state in the patient group. Bipolar subjects were administered the Structured Clinical Interview for DSM-IV (SCID), Hamilton Rating Scale for Depression, and Clinician-Administered Rating Scale for Mania. Controls received the SCID, a family psychiatric history questionnaire, and urine toxicology screen to confirm healthy status. Both groups competed the 240-item Temperament and Character Inventory (TCI). A multivariate analysis of covariance, accounting for demographic factors, was conducted to compare the groups on the TCI. Bipolar I patients scored higher on harm avoidance, lower on self-directedness, and higher on self-transcendence compared to controls. Harm avoidance and self-directedness were correlated with residual depressive symptoms positively and negatively, respectively;...Continue Reading

References

Apr 1, 1989·Archives of General Psychiatry·R M HirschfeldW Coryell
Jul 1, 1983·Archives of General Psychiatry·H S AkiskalB I Yerevanian
Jun 1, 1983·The American Journal of Psychiatry·R M HirschfeldB H Larkin
Dec 1, 1993·Archives of General Psychiatry·C R CloningerT R Przybeck
Jun 1, 1993·The American Journal of Psychiatry·R T JoffeJ D Parker
Sep 9, 1996·Journal of Affective Disorders·D A SolomonM B Keller
Jun 11, 1999·Journal of Affective Disorders·Y OsherM Kotler
Mar 30, 2000·European Archives of Psychiatry and Clinical Neuroscience·J RichterG Richter
Sep 20, 2001·The Journal of Clinical Psychiatry·I K LyooJ S Kwon
Jun 5, 2002·Archives of General Psychiatry·Lewis L JuddMartin B Keller
May 14, 2003·Archives of General Psychiatry·Anne FarmerPeter McGuffin
Feb 1, 1960·Journal of Neurology, Neurosurgery, and Psychiatry·M HAMILTON
Oct 7, 2004·Journal of Affective Disorders·Christer EngströmPer-Olof Nylander
Feb 24, 2005·Psychological Medicine·Kelly L KlumpWalter H Kaye
Mar 23, 2005·Journal of Affective Disorders·Cecylia NowakowskaTerence A Ketter

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Citations

Oct 12, 2010·Current Psychiatry Reports·Shefali Srivastava, Terence A Ketter
Mar 4, 2011·Psychiatric Genetics·Ney Alliey-RodriguezElliot S Gershon
Mar 16, 2013·Brain Structure & Function·Daniela LaricchiutaGianfranco Spalletta
Jul 27, 2011·Depression Research and Treatment·James A HarleyPeter R Joyce
Jun 26, 2012·Comprehensive Psychiatry·Gökhan SarısoyAhmet Rifat Sahin
May 14, 2011·Comprehensive Psychiatry·Jouko Miettunen, Anu Raevuori
Jun 2, 2009·Brain Research Bulletin·Simona GardiniAnnalena Venneri
Apr 4, 2009·Journal of Pharmacological and Toxicological Methods·Shlomit Flaisher-Grinberg, Haim Einat
May 30, 2009·Clinical Psychology & Psychotherapy·Marianne HalvorsenKnut Waterloo
Nov 17, 2011·Bipolar Disorders·Karla Mathias AlmeidaBeny Lafer
Sep 12, 2012·Human Brain Mapping·Daniela LaricchiutaGianfranco Spalletta
Aug 27, 2013·Journal of Affective Disorders·Tiffany A GreenwoodJohn R Kelsoe
Jun 24, 2011·European Psychiatry : the Journal of the Association of European Psychiatrists·T Hirvikoski, J Jokinen
Jun 16, 2016·Journal of Psychiatric Research·Isabelle E BauerJair C Soares
Oct 22, 2016·Journal of Child and Adolescent Psychopharmacology·Eunjoo KimManpreet K Singh
Apr 2, 2015·Revista da Escola de Enfermagem da U S P·Naraiana de Oliveira TavaresLeandro Fernandes Malloy-Diniz
Jan 22, 2018·Journal of Religion and Health·John R Peteet
Mar 8, 2018·Social Psychiatry and Psychiatric Epidemiology·Cristiane S PaulaEvandro Silva Freire Coutinho
Nov 6, 2012·The Journal of Nervous and Mental Disease·Kyoung-Sae NaShin-Gyeom Kim
Nov 21, 2020·Clinical Psychology Review·Benjamin A KatzIftah Yovel
Aug 21, 2018·NeuroImage·Rongtao JiangJing Sui

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Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.