Temperature-dependent growth contributes to long-term cold sensing.

Nature
Yusheng ZhaoMartin Howard

Abstract

Temperature is a key factor in the growth and development of all organisms1,2. Plants have to interpret temperature fluctuations, over hourly to monthly timescales, to align their growth and development with the seasons. Much is known about how plants respond to acute thermal stresses3,4, but the mechanisms that integrate long-term temperature exposure remain unknown. The slow, winter-long upregulation of VERNALIZATION INSENSITIVE 3 (VIN3)5-7, a PHD protein that functions with Polycomb repressive complex 2 to epigenetically silence FLOWERING LOCUS C (FLC) during vernalization, is central to plants interpreting winter progression5,6,8-11. Here, by a forward genetic screen, we identify two dominant mutations of the transcription factor NTL8 that constitutively activate VIN3 expression and alter the slow VIN3 cold induction profile. In the wild type, the NTL8 protein accumulates slowly in the cold, and directly upregulates VIN3 transcription. Through combining computational simulation and experimental validation, we show that a major contributor to this slow accumulation is reduced NTL8 dilution due to slow growth at low temperatures. Temperature-dependent growth is thus exploited through protein dilution to provide the long-term ...Continue Reading

References

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Citations

Jul 17, 2020·Nature·Hiroyuki Iida, Ari Pekka Mähönen
Dec 29, 2020·Frontiers in Plant Science·Yuan SongLizhe An
Jan 29, 2021·Current Opinion in Plant Biology·Kaixuan HeXian Deng
Feb 16, 2021·Frontiers in Plant Science·Rea L Antoniou-KourouniotiMartin Howard
Jan 21, 2021·International Journal of Molecular Sciences·Gaojie LiHongwei Hou
Mar 5, 2021·Current Opinion in Plant Biology·Govind MenonMartin Howard
Mar 9, 2021·Frontiers in Plant Science·Wim J J SoppeMaria C Albani
Oct 24, 2020·Trends in Genetics : TIG·Richard W Carthew
May 15, 2021·Genes & Development·Yusheng ZhaoCaroline Dean
Jun 3, 2021·Genes & Development·Yu Jin, Sebastian Marquardt
Jun 3, 2021·International Journal of Molecular Sciences·Stella QuirozBerenice García-Ponce
Jun 4, 2021·Journal of Experimental Botany·Christian Danve M Castroverde, Damaris Dina
May 30, 2021·Journal of Experimental Botany·Saurabh Prakash PandeyMarkus Schmid
Oct 28, 2020·Developmental Cell·Changxuan Li, Xiaofeng Fang

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Methods Mentioned

BETA
transgenic
PCR
immunoprecipitation
transgenics
fluorescence imaging
X-ray
ChIP
chemical treatments
Fluorescence microscopy

Software Mentioned

Alphaimager
ImageJ

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